SCHEMBL30772134

SCHEMBL30772134

COc1ncc(-c2ccc(F)c(C)c2)c(N2CCC(c3nc[nH]c3C)CC2)n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ SLC9A1 P19634 20/20 1.00
▸ SLC9A2 Q9UBY0 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14276839 1.00 SLC9A1 (1.00) SLC9A1SLC9A2
SCHEMBL14276752 0.91 SLC9A1 (1.00) SLC9A1SLC9A2
SCHEMBL14276853 0.90 SLC9A1 (1.00) SLC9A1SLC9A2
SCHEMBL14276830 0.87 SLC9A1 (0.80) SLC9A1SLC9A2
SCHEMBL16588925 0.86 SLC9A1 (0.76) SLC9A1SLC9A2
SCHEMBL14276835 0.86 SLC9A1 (0.85) SLC9A1SLC9A2
SCHEMBL14276832 0.85 SLC9A1 (0.77) SLC9A1SLC9A2
SCHEMBL14276838 0.85 SLC9A1 (0.74) SLC9A1SLC9A2
SCHEMBL14276871 0.84 SLC9A1 (0.72) SLC9A1SLC9A2
SCHEMBL14276741 0.84 SLC9A1 (1.00) SLC9A1SLC9A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4577202-A1 USE OF A THERAPEUTIC AGENT WITH SODIUM-HYDROGEN ANTIPORTER 1 INHIBITORY ACTIVITY FOR THE TREATMENT AND PREVENTION OF DISEASES ASSOCIATED WITH CHRONIC FATIGUE, EXHAUSTION AND/OR EXERTIONAL INTOLERANCE Mitodicure GmbH (DE) 2025-07-02 — — EP claimed
CN-119923254-A Use of therapeutic agents having sodium hydrogen antiport 1 inhibitory activity for the treatment and prevention of diseases associated with chronic fatigue, exhaustion and/or fatigue intolerance 米托迪治愈有限责任公司 2025-05-02 — — CN claimed
WO-2024042160-A1 USE OF A THERAPEUTIC AGENT WITH SODIUM-HYDROGEN ANTIPORTER 1 INHIBITORY ACTIVITY FOR THE TREATMENT AND PREVENTION OF DISEASES ASSOCIATED WITH CHRONIC FATIGUE, EXHAUSTION AND/OR EXERTIONAL INTOLERANCE MITODICURE GMBH (DE) 2024-02-29 — — WO claimed
EP-4577202-A1 USE OF A THERAPEUTIC AGENT WITH SODIUM-HYDROGEN ANTIPORTER 1 INHIBITORY ACTIVITY FOR THE TREATMENT AND PREVENTION OF DISEASES ASSOCIATED WITH CHRONIC FATIGUE, EXHAUSTION AND/OR EXERTIONAL INTOLERANCE Mitodicure GmbH (DE) 2025-07-02 — — EP disclosed
CN-119923254-A Use of therapeutic agents having sodium hydrogen antiport 1 inhibitory activity for the treatment and prevention of diseases associated with chronic fatigue, exhaustion and/or fatigue intolerance 米托迪治愈有限责任公司 2025-05-02 — — CN disclosed
WO-2024042160-A1 USE OF A THERAPEUTIC AGENT WITH SODIUM-HYDROGEN ANTIPORTER 1 INHIBITORY ACTIVITY FOR THE TREATMENT AND PREVENTION OF DISEASES ASSOCIATED WITH CHRONIC FATIGUE, EXHAUSTION AND/OR EXERTIONAL INTOLERANCE MITODICURE GMBH (DE) 2024-02-29 — — WO disclosed
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