Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 7/20 | 0.69 |
| ▸ | F2 | P00734 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | LTA4H | P09960 | 1/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.57 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18459237 | 0.83 | BCHE (0.69) | BCHEF2KCNH2GRIN2BMEN1 | |
| SCHEMBL2157904 | 0.83 | BCHE (0.69) | BCHEF2KCNH2GRIN2BMEN1 | |
| SCHEMBL13894608 | 0.83 | BCHE (0.69) | BCHEF2KCNH2GRIN2BMEN1 | |
| Hydrochloric Acid SCHEMBL4451835 | 0.81 | BCHE (0.67) | BCHEF2KCNH2GRIN2BMEN1 | |
| SCHEMBL2587466 | 0.81 | BCHE (1.00) | BCHEMEN1KMT2A | |
| SCHEMBL3932679 | 0.81 | ALDH1A1 (0.58) | KCNH2LMNACYP1A2PTGS1SLC6A2 | |
| Hydrochloric Acid SCHEMBL4456317 | 0.80 | BCHE (0.97) | BCHEMEN1KMT2A | |
| SCHEMBL13886610 | 0.80 | BCHE (0.74) | BCHEF2KCNH2GRIN2BMEN1 | |
| SCHEMBL27960960 | 0.79 | F2 (0.78) | BCHEF2KCNH2GRIN2BMEN1 | |
| SCHEMBL10609652 | 0.79 | LMNA (0.75) | BCHELTA4HEPHX2FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7339079-B2 | Thyronamine derivatives and analogs and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-03-04 | — | — | US | disclosed |