Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.49 |
| ▸ | BRD4 | O60885 | 2/20 | 0.48 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL599782 | 1.00 | TRPV1 (0.49) | TRPV1BRD4CREBBPMAPK1CNR1 | |
| SCHEMBL14452760 | 1.00 | TRPV1 (0.49) | TRPV1BRD4CREBBPMAPK1CNR1 | |
| SCHEMBL803487 | 1.00 | TRPV1 (0.49) | TRPV1BRD4CREBBPMAPK1CNR1 | |
| SCHEMBL4226632 | 0.87 | TRPV1 (0.54) | TRPV1BRD4CREBBPMAPK1CNR1 | |
| SCHEMBL4226634 | 0.87 | TRPV1 (0.54) | TRPV1BRD4CREBBPMAPK1CNR1 | |
| SCHEMBL26962614 | 0.85 | TRPV1 (0.50) | TRPV1BRD4CREBBPMAPK1CNR1 | |
| SCHEMBL27125516 | 0.85 | TRPV1 (0.50) | TRPV1BRD4CREBBPMAPK1CNR1 | |
| SCHEMBL20622055 | 0.84 | TRPV1 (0.49) | TRPV1BRD4CREBBPMAPK1CNR1 | |
| SCHEMBL31316828 | 0.84 | TRPV1 (0.49) | TRPV1BRD4CREBBPMAPK1CNR1 | |
| SCHEMBL21376365 | 0.83 | XIAP (0.53) | TRPV1BRD4CREBBPMAPK1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008027740-A2 | CATALYTIC ASYMMETRIC SYNTHESIS OF PRIMARY AMINES VIA BORANE REDUCTION OF OXIME ETHERS USING SPIROBORATE ESTERS | OFFICE OF INTELLECTUAL PROPERTY AND TECHNOLOGY (US) | 2008-03-06 | — | — | WO | disclosed |