Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.46 |
| ▸ | BRD4 | O60885 | 2/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.46 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4226632 | 0.87 | TRPV1 (0.54) | TRPV1CNR1CNR2MAPK1BRD4 | |
| SCHEMBL4226634 | 0.87 | TRPV1 (0.54) | TRPV1CNR1CNR2MAPK1BRD4 | |
| SCHEMBL26962614 | 0.85 | TRPV1 (0.50) | TRPV1CNR1CNR2MAPK1BRD4 | |
| SCHEMBL27125516 | 0.85 | TRPV1 (0.50) | TRPV1CNR1CNR2MAPK1BRD4 | |
| SCHEMBL31316828 | 0.84 | TRPV1 (0.49) | TRPV1CNR1CNR2MAPK1BRD4 | |
| SCHEMBL14452760 | 0.84 | TRPV1 (0.49) | TRPV1CNR1CNR2MAPK1BRD4 | |
| SCHEMBL599782 | 0.84 | TRPV1 (0.49) | TRPV1CNR1CNR2MAPK1BRD4 | |
| SCHEMBL803487 | 0.84 | TRPV1 (0.49) | TRPV1CNR1CNR2MAPK1BRD4 | |
| SCHEMBL14277888 | 0.84 | TRPV1 (0.49) | TRPV1CNR1CNR2MAPK1BRD4 | |
| SCHEMBL30563608 | 0.81 | HTT (0.57) | TRPV1CNR1CNR2BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019002132-A1 | NEW AZAQUINOLINE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2019-01-03 | — | — | WO | disclosed |