Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.49 |
| ▸ | BRD4 | O60885 | 2/20 | 0.48 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14452760 | 1.00 | TRPV1 (0.49) | TRPV1BRD4CREBBPMAPK1CNR1 | |
| SCHEMBL803487 | 1.00 | TRPV1 (0.49) | TRPV1BRD4CREBBPMAPK1CNR1 | |
| SCHEMBL14277888 | 1.00 | TRPV1 (0.49) | TRPV1BRD4CREBBPMAPK1CNR1 | |
| SCHEMBL4226632 | 0.87 | TRPV1 (0.54) | TRPV1BRD4CREBBPMAPK1CNR1 | |
| SCHEMBL4226634 | 0.87 | TRPV1 (0.54) | TRPV1BRD4CREBBPMAPK1CNR1 | |
| SCHEMBL26962614 | 0.85 | TRPV1 (0.50) | TRPV1BRD4CREBBPMAPK1CNR1 | |
| SCHEMBL27125516 | 0.85 | TRPV1 (0.50) | TRPV1BRD4CREBBPMAPK1CNR1 | |
| SCHEMBL20622055 | 0.84 | TRPV1 (0.49) | TRPV1BRD4CREBBPMAPK1CNR1 | |
| SCHEMBL31316828 | 0.84 | TRPV1 (0.49) | TRPV1BRD4CREBBPMAPK1CNR1 | |
| SCHEMBL21376365 | 0.83 | XIAP (0.53) | TRPV1BRD4CREBBPMAPK1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3204360-B1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | GENENTECH INC (US) | 2020-08-26 | — | — | EP | disclosed |
| US-20170312292-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | WUXI APPTEC (SHANGHAI) CO. LTD (CN) | 2017-11-02 | — | — | US | disclosed |
| WO-2016055028-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2016-04-14 | — | — | WO | disclosed |
| EP-1592674-B1 | AMINO 1, 3, 5-TRIAZINES N-SUBSTITUTED WITH CHIRAL BICYCLIC RADICALS, PROCESS FOR THEIR PREPARATION, COMPOSITIONS THEREOF AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AG (DE) | 2014-03-05 | — | — | EP | disclosed |
| US-20120101287-A1 | Amino-1,3,5-triazines N-substituted with chiral bicyclic radicals, process for their preparation, compositions thereof, and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2012-04-26 | — | — | US | disclosed |
| US-8114991-B2 | Used for the control of a range of harmful weeds | BAYER CROPSCIENCE AG (DE) | 2012-02-14 | — | — | US | disclosed |
| EP-2305655-A2 | Amino-1,3,5-triazines N-substituted with chiral bicyclic radicals, process for their preparation, compositions thereof, and their use as herbicides and plant growth regulators. | Bayer CropScience AG (DE) | 2011-04-06 | — | — | EP | disclosed |
| US-7592488-B2 | Method for preparing optically active amines | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2009-09-22 | — | — | US | disclosed |
| US-7592488-B2 | Method for preparing optically active amines | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2009-09-22 | — | — | US | disclosed |
| US-20090035830-A1 | Method for Preparing Optically Active Amines | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2009-02-05 | — | — | US | disclosed |
| US-20090035830-A1 | Method for Preparing Optically Active Amines | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2009-02-05 | — | — | US | disclosed |
| EP-1592674-A1 | AMINO 1, 3, 5-TRIAZINES N-SUBSTITUTED WITH CHIRAL BICYCLIC RADICALS, PROCESS FOR THEIR PREPARATION, COMPOSITIONS THEREOF AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | Bayer CropScience GmbH (DE) | 2005-11-09 | — | — | EP | disclosed |
| WO-2004069814-A1 | AMINO 1, 3, 5-TRIAZINES N-SUBSTITUTED WITH CHIRAL BICYCLIC RADICALS, PROCESS FOR THEIR PREPARATION, COMPOSITIONS THEREOF AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE GMBH (DE) | 2004-08-19 | — | — | WO | disclosed |
| US-20040157739-A1 | Amino-1,3,5-triazines N-substituted with chiral bicyclic radicals, process for their preparation, compositions thereof, and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157739-A1 | Amino-1,3,5-triazines N-substituted with chiral bicyclic radicals, process for their preparation, compositions thereof, and their use as herbicides and plant growth regulators | CYP4Z1, IL4I1, BCAT1 | TRPV1 4557/4885BRD4 835/4885CREBBP 3299/4885 |
| US-20120101287-A1 | Amino-1,3,5-triazines N-substituted with chiral bicyclic radicals, process for their preparation, compositions thereof, and their use as herbicides and plant growth regulators | IL4I1, DAO, CYP4Z1 | TRPV1 4298/4885BRD4 1439/4885CREBBP 3727/4885 |
| US-20170312292-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | EP300, CREBBP, HDAC1 | TRPV1 1398/4885BRD4 18/4885CREBBP 2/4885 |
| US-20090035830-A1 | Method for Preparing Optically Active Amines | CEL, NAAA, LIPA | TRPV1 3880/4885BRD4 2240/4885CREBBP 2108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.