SCHEMBL1427824

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19112901	0.92	KCNH2 (0.56)	KCNH2CACNA1IMCHR1SMYD3HTR1A
	SCHEMBL16478281	0.90	KCNH2 (0.54)	KCNH2CACNA1IMCHR1SMYD3HTR1A
	SCHEMBL30864972	0.90	KCNH2 (0.67)	KCNH2CACNA1IMCHR1HTR1AADRA2A
	SCHEMBL11712708	0.87	HDAC6 (0.56)	KCNH2CACNA1IMCHR1SMYD3HDAC6
	Hydrochloric Acid SCHEMBL11715522	0.86	HDAC6 (0.55)	KCNH2CACNA1IMCHR1SMYD3HDAC6
	SCHEMBL13568433	0.86	KCNH2 (0.62)	KCNH2CACNA1IMCHR1HTR1AADRA2A
	SCHEMBL3890171	0.84	KCNH2 (0.61)	KCNH2CACNA1IMCHR1HTR1AADRA2A
	SCHEMBL3890167	0.84	KCNH2 (0.61)	KCNH2CACNA1IMCHR1HTR1AADRA2A
	SCHEMBL15244626	0.84	SCN9A (0.69)	KCNH2CACNA1ISMYD3SCN9AHDAC6
	SCHEMBL15229266	0.84	ITGB3 (0.50)	KCNH2CACNA1IMCHR1SMYD3HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.