SCHEMBL1428

SCHEMBL1428

C=CCOc1ccccc1C(=O)Cl

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIG1 P18858 1/20 0.67
TSHR P16473 3/20 0.53
GAA P10253 3/20 0.53
CYP3A4 P08684 2/20 0.51
KDM4E B2RXH2 1/20 0.50
ADRB2 P07550 2/20 0.49
ADRB1 P08588 2/20 0.49
ADRB3 P13945 1/20 0.49
HSD17B10 Q99714 2/20 0.49
HPGD P15428 1/20 0.49
MAPK1 P28482 1/20 0.49
ALDH1A1 P00352 2/20 0.45
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
SLC22A1 O15245 1/20 0.41
LMNA P02545 1/20 0.41
CYP1A2 P05177 1/20 0.41
HTR1A P08908 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9696302 0.86 LIG1 (0.71) LIG1TSHRGAACYP3A4KDM4E
SCHEMBL28233354 0.85 LIG1 (0.54) LIG1TSHRGAACYP3A4KDM4E
SCHEMBL40310 0.84 LIG1 (0.69) LIG1TSHRGAACYP3A4KDM4E
SCHEMBL29519569 0.84 LIG1 (0.69) LIG1TSHRGAACYP3A4KDM4E
SCHEMBL28696012 0.83 LIG1 (0.77) LIG1TSHRGAACYP3A4KDM4E
SCHEMBL2788250 0.83 LIG1 (0.67) LIG1TSHRGAACYP3A4KDM4E
SCHEMBL18259145 0.83 LIG1 (0.67) LIG1TSHRGAACYP3A4KDM4E
SCHEMBL1889645 0.83 LIG1 (0.67) LIG1TSHRGAACYP3A4KDM4E
SCHEMBL1426602 0.83 LIG1 (0.67) LIG1TSHRGAACYP3A4KDM4E
SCHEMBL7794511 0.83 LIG1 (0.67) LIG1TSHRGAACYP3A4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117757078-A Polymer, modified epoxy resin containing same, and preparation method and application thereof 中国石油化工股份有限公司 2024-03-26 CN claimed
CN-112251240-B Quaternary ammonium salt ionic liquid crystal polymer with temperature control electronic switch performance and preparation method and application thereof 东北大学 2022-04-12 CN claimed
CN-112251240-A Quaternary ammonium salt ionic liquid crystal polymer with temperature control electronic switch performance and preparation method and application thereof 东北大学 2021-01-22 CN claimed
CN-117757078-A Polymer, modified epoxy resin containing same, and preparation method and application thereof 中国石油化工股份有限公司 2024-03-26 CN disclosed
CN-112251240-B Quaternary ammonium salt ionic liquid crystal polymer with temperature control electronic switch performance and preparation method and application thereof 东北大学 2022-04-12 CN disclosed
CN-109467722-B LCP film for FPC industry and preparation method thereof 苏州市新广益电子有限公司 2022-04-08 CN disclosed
CN-113201008-B Full-spectrum selective reflection cyclic side chain liquid crystal oligomer film and preparation method thereof 徐州工程学院 2021-11-09 CN disclosed
CN-111961540-B Preparation process of decontamination type washing powder 广州浪奇日用品有限公司 2021-08-31 CN disclosed
CN-113201008-A Full-spectrum selective reflection cyclic side chain liquid crystal oligomer film and preparation method thereof 徐州工程学院 2021-08-03 CN disclosed
CN-112251240-A Quaternary ammonium salt ionic liquid crystal polymer with temperature control electronic switch performance and preparation method and application thereof 东北大学 2021-01-22 CN disclosed
CN-111961540-A Preparation process of efficient decontamination type washing powder 广州浪奇日用品有限公司 2020-11-20 CN disclosed
US-5654471-A Process for the preparation of 4-hydroxyphenyl benzoate derivatives CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1997-08-05 US disclosed
CN-1028758-C Pyrazolopyrimidinone antianginal agents PFIZER (US) 1995-06-07 CN disclosed
EP-0463756-B1 Pyrazolopyrimidinone antianginal agents PFIZER LTD (GB) 1995-04-19 EP disclosed
US-5346901-A Treatment of angina, hypertension, heart failure and atherosclerosis PFIZER INC. (US) 1994-09-13 US disclosed
US-5250534-A Inhibitors of cyclic guanosine 3*,5*-monophosphate phosphodiesterase PFIZER INC. (US) 1993-10-05 US disclosed
EP-0463756-A1 Pyrazolopyrimidinone antianginal agents Pfizer Limited (GB) 1992-01-02 EP disclosed
CN-1057464-A Pyrazolopyrimidinoneantianginal antianginal agents PFIZER (US) 1992-01-01 CN disclosed
EP-0060335-B1 COMPOSITIONS BASED ON CYCLIC ORGANOPOLYSILOXANES FORMING LIQUID CRYSTAL PHASES, THEIR MANUFACTURE AND THEIR USE Consortium für elektrochemische Industrie GmbH (DE) 1983-12-28 EP disclosed
EP-0060335-A1 Compositions based on cyclic organopolysiloxanes forming liquid crystal phases, their manufacture and their use Consortium für elektrochemische Industrie GmbH (DE) 1982-09-22 EP disclosed