Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIG1 | P18858 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1131998 | 0.97 | LIG1 (0.67) | LIG1KDM4ECYP3A4ADRB2ADRB1 | |
| SCHEMBL669636 | 0.97 | LIG1 (0.67) | LIG1KDM4ECYP3A4ADRB2ADRB1 | |
| SCHEMBL7068224 | 0.97 | LIG1 (0.67) | LIG1KDM4ECYP3A4ADRB2ADRB1 | |
| Zinc Ion SCHEMBL2788244 | 0.97 | LIG1 (0.67) | LIG1KDM4ECYP3A4ADRB2ADRB1 | |
| SCHEMBL18259145 | 0.97 | LIG1 (0.67) | LIG1KDM4ECYP3A4ADRB2ADRB1 | |
| SCHEMBL1426602 | 0.97 | LIG1 (0.67) | LIG1KDM4ECYP3A4ADRB2ADRB1 | |
| SCHEMBL28253072 | 0.86 | LIG1 (0.67) | LIG1KDM4ECYP3A4ADRB2ADRB1 | |
| SCHEMBL3798396 | 0.86 | KDM4E (0.71) | LIG1KDM4ECYP3A4ADRB2ADRB1 | |
| SCHEMBL9696302 | 0.86 | LIG1 (0.71) | LIG1KDM4ECYP3A4ADRB2ADRB1 | |
| SCHEMBL40310 | 0.84 | LIG1 (0.69) | LIG1KDM4ECYP3A4ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 808 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12031103-B2 | Method of limiting chemical degradation due to nitrogen dioxide contamination | INFINEUM INTERNATIONAL LTD (GB) | 2024-07-09 | — | — | US | claimed |
| CN-118291197-A | Lubricating grease and preparation method and application thereof | 杭州得润宝油脂股份有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-118146862-A | Wind power gear oil composition and preparation method thereof | 季华实验室 | 2024-06-07 | — | — | CN | claimed |
| CN-118126764-A | Lubricating oil for restoring expansion force of piston ring and having no oil dirt and preparation method thereof | 普朗克量子科技(天津)有限公司 | 2024-06-04 | — | — | CN | claimed |
| CN-117925299-A | Ultralow-temperature shearing-resistant hydraulic oil composition and preparation method thereof | 中国石油化工股份有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-117903862-A | Lubricating oil composition | 英菲诺姆国际有限公司 | 2024-04-19 | — | — | CN | claimed |
| CN-117778082-A | Lubricating oil composition for plug-in hybrid electric vehicle gearbox and preparation method thereof | 中国石油化工股份有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-117660075-A | Grease for maintenance-free bearing of oil pumping unit | 中国石油化工股份有限公司 | 2024-03-08 | — | — | CN | claimed |
| CN-117535087-A | Preparation method of lubricating oil additive containing single-layer or oligolayer graphene | 中海油气(泰州)石化有限公司 | 2024-02-09 | — | — | CN | claimed |
| CN-115851337-B | Preparation method of alkaline calcium alkyl salicylate | 新乡市瑞丰新材料股份有限公司 | 2023-12-22 | — | — | CN | claimed |
| EP-0651043-A2 | Grease compositions | The Lubrizol Corporation (US) | 1995-05-03 | — | — | EP | claimed |
| US-5362409-A | Thiophosphorus acid ester | THE LUBRIZOL CORPORATION (US) | 1994-11-08 | — | — | US | claimed |
| EP-0580335-A1 | Grease compositions | The Lubrizol Corporation (US) | 1994-01-26 | — | — | EP | claimed |
| US-5256320-A | Overbased metal salts, thiophosphates, and phosphites blended | THE LUBRIZOL CORPORATION (US) | 1993-10-26 | — | — | US | claimed |
| CN-1076475-A | Load with the renovation process of the large-scale set lubricant oil of lotus | LUO ZIHUI (CN) | 1993-09-22 | — | — | CN | claimed |
| EP-0227182-B1 | CREASE COMPOSITION | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-02-06 | — | — | EP | claimed |
| US-4719023-A | OVERBASED CALCIUM ALKYLSALICYLATE | SHELL OIL COMPANY (US) | 1988-01-12 | — | — | US | claimed |
| EP-0227182-A2 | Crease composition | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1987-07-01 | — | — | EP | claimed |
| CN-85101591-A | IC engine oil additive component | — | 1987-03-04 | — | — | CN | claimed |
| US-4251431-A | COMPRISING A PERFLUOROALKYL POLYETHER, A METHYLPOLYSILOXANE AND A POLYTETRAFLUOROETHYLENE THICKENER | SHELL OIL COMPANY (US) | 1981-02-17 | — | — | US | claimed |