Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | FPR3 | P25089 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25795585 | 0.89 | HDAC6 (0.36) | GBA1PDK2HDAC6CA14HDAC1 | |
| SCHEMBL10260946 | 0.84 | HDAC6 (0.40) | GBA1PDK2HDAC6CA14HDAC1 | |
| SCHEMBL19699862 | 0.83 | CHRM2 (0.39) | GBA1PDK2HDAC6CA14HDAC1 | |
| SCHEMBL14444126 | 0.81 | BCHE (0.35) | GBA1PDK2HDAC6CA14HDAC1 | |
| SCHEMBL25736655 | 0.81 | HDAC6 (0.38) | GBA1PDK2HDAC6CA14HDAC1 | |
| SCHEMBL21137604 | 0.80 | GBA1 (0.34) | GBA1PDK2HDAC6CA14HDAC1 | |
| SCHEMBL19088681 | 0.79 | GBA1 (0.36) | GBA1PDK2HDAC6CA14HDAC1 | |
| SCHEMBL25479216 | 0.78 | CA14 (0.42) | GBA1PDK2HDAC6CA14HDAC1 | |
| SCHEMBL18257000 | 0.78 | CA14 (0.42) | GBA1PDK2HDAC6CA14HDAC1 | |
| SCHEMBL19607386 | 0.77 | CA14 (0.39) | GBA1PDK2HDAC6CA14HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7314959-B2 | Amino thiol compounds and compositions for use in conjunction with cancer therapy | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-01-01 | — | — | US | disclosed |
| US-7314959-B2 | Amino thiol compounds and compositions for use in conjunction with cancer therapy | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-01-01 | — | — | US | disclosed |