Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | FPR3 | P25089 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10260946 | 0.86 | HDAC6 (0.40) | GBA1HDAC6CHRNB2CHRNA4CA14 | |
| SCHEMBL22303932 | 0.83 | NFKB1 (0.43) | GBA1HDAC6CHRNB2CHRNA4CA14 | |
| SCHEMBL25795585 | 0.82 | HDAC6 (0.36) | GBA1HDAC6CHRNB2CHRNA4CA14 | |
| SCHEMBL22651094 | 0.81 | PDK2 (0.36) | GBA1HDAC6CHRNB2CHRNA4CA14 | |
| SCHEMBL15356403 | 0.81 | GBA1 (0.34) | GBA1HDAC6CHRNB2CHRNA4CA14 | |
| SCHEMBL19088681 | 0.81 | GBA1 (0.36) | GBA1HDAC6CA14HDAC1HDAC2 | |
| SCHEMBL19699862 | 0.80 | CHRM2 (0.39) | GBA1HDAC6CHRNB2CHRNA4CA14 | |
| SCHEMBL14280284 | 0.80 | GBA1 (0.34) | GBA1HDAC6CA14HDAC1HDAC2 | |
| SCHEMBL25736655 | 0.79 | HDAC6 (0.38) | GBA1HDAC6CHRNB2CHRNA4CA14 | |
| SCHEMBL20762898 | 0.79 | GBA1 (0.39) | GBA1HDAC6CA14HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10328161-B2 | Luciferin derivatives from bicyclic reactants and aminothiol derivatives and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10328161-B2 | Luciferin derivatives from bicyclic reactants and aminothiol derivatives and methods of use thereof | GFPT1, QPCT, GLB1 | GBA1 670/4885HDAC6 4816/4885CHRNB2 3715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.