Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA7 | P43166 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 6/20 | 0.34 |
| ▸ | CTSS | P25774 | 4/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.34 |
| ▸ | APLNR | P35414 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6823074 | 0.88 | TDP1 (0.46) | TDP1MEN1GAAKMT2ACA1 | |
| SCHEMBL3795863 | 0.85 | APLNR (0.38) | TDP1MEN1GAAKMT2ACA1 | |
| SCHEMBL78913 | 0.82 | TDP1 (0.42) | TDP1MEN1GAAKMT2ACA1 | |
| SCHEMBL25351697 | 0.79 | MEN1 (0.38) | TDP1MEN1GAAKMT2ACA1 | |
| SCHEMBL14280308 | 0.79 | TDP1 (0.47) | TDP1MEN1GAAKMT2ACA1 | |
| SCHEMBL15584689 | 0.79 | CA2 (0.34) | TDP1MEN1GAAKMT2ACA1 | |
| SCHEMBL1437011 | 0.78 | TDP1 (0.40) | TDP1MEN1GAAKMT2ACA1 | |
| SCHEMBL3787958 | 0.77 | CA12 (0.48) | KMT2ACA1CA7CTSKCTSS | |
| SCHEMBL18254602 | 0.77 | TDP1 (0.38) | TDP1MEN1GAAKMT2ACA1 | |
| Hydrochloric Acid SCHEMBL28622640 | 0.76 | TDP1 (0.39) | TDP1MEN1GAAKMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7314959-B2 | Amino thiol compounds and compositions for use in conjunction with cancer therapy | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-01-01 | — | — | US | disclosed |
| US-7314959-B2 | Amino thiol compounds and compositions for use in conjunction with cancer therapy | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-01-01 | — | — | US | disclosed |