Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.54 |
| ▸ | TACR1 | P25103 | 1/20 | 0.54 |
| ▸ | GRM5 | P41594 | 1/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13841236 | 0.85 | GAA (0.57) | ACHEALDH1A1SMN1; SMN2L3MBTL1GAA | |
| SCHEMBL7467929 | 0.84 | ALDH1A1 (0.77) | ALDH1A1POLBSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL13597199 | 0.83 | TACR1 (0.57) | ALDH1A1POLBSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL10666731 | 0.82 | ALDH1A1 (0.56) | ALDH1A1POLBSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11195264 | 0.80 | ALDH1A1 (0.83) | ALDH1A1POLBSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL10670574 | 0.79 | ALDH1A1 (0.66) | ALDH1A1POLBSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11661567 | 0.79 | ALDH1A1 (0.87) | ALDH1A1POLBSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL13597201 | 0.78 | TACR1 (0.62) | ALDH1A1POLBSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL13841268 | 0.76 | GAA (0.51) | ACHESMN1; SMN2KMT2AGAAAGTR2 | |
| SCHEMBL3310703 | 0.76 | ALDH1A1 (0.61) | ALDH1A1POLBSMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008025857-A2 | NEW METHOD FOR THE TREATMENT OF INFLAMMATORY DISEASES | TOPOTARGET SWITZERLAND SA (CH) | 2008-03-06 | — | — | WO | disclosed |