SCHEMBL14280389

SCHEMBL14280389

CCCCn1c2cc(OC)c(OC)cc2c(=O)c2cc(OC)c(OC)cc21

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PGR P06401 5/20 0.46
RORA P35398 3/20 0.46
RORC P51449 3/20 0.46
RORB Q92753 3/20 0.46
TP53 P04637 2/20 0.43
ALDH1A1 P00352 4/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
KDM4E B2RXH2 2/20 0.40
HSD17B10 Q99714 2/20 0.40
HPGD P15428 1/20 0.40
PIM1 P11309 1/20 0.40
PDE3B Q13370 1/20 0.39
PDE3A Q14432 1/20 0.39
DYRK1A Q13627 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14280385 0.90 PGR (0.52) PGRRORARORCRORBALDH1A1
SCHEMBL14315155 0.86 KDM4E (0.42) PGRRORARORCRORBALDH1A1
SCHEMBL14160805 0.78 KDM4E (0.62) PGRRORARORCRORBALDH1A1
SCHEMBL12328356 0.78 PSEN1 (0.43) TP53ALDH1A1MEN1KMT2AKDM4E
SCHEMBL14160816 0.78 DYRK1A (0.57) PGRRORARORCRORBALDH1A1
SCHEMBL14280398 0.78 PGR (0.51) PGRRORARORCRORBALDH1A1
SCHEMBL14160813 0.77 KDM4E (0.57) PGRRORARORCRORBKDM4E
SCHEMBL14280402 0.77 KDM4E (0.37) PGRRORARORCRORBALDH1A1
SCHEMBL21915048 0.75 PIM1 (0.50) PGRRORARORCRORBALDH1A1
SCHEMBL29431065 0.75 PIM1 (0.50) PGRRORARORCRORBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080020323-A1 Light sensitive planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2008-01-24 US disclosed
US-20080020323-A1 Light sensitive planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2008-01-24 US disclosed