SCHEMBL14280385

SCHEMBL14280385

CCCCn1c2ccccc2c(=O)c2cc(OC)c(OC)cc21

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 3/20 0.52
RORA P35398 3/20 0.52
RORC P51449 3/20 0.52
RORB Q92753 3/20 0.52
ALDH1A1 P00352 2/20 0.51
SLC6A4 P31645 2/20 0.50
SLC6A2 P23975 1/20 0.50
KCNA3 P22001 1/20 0.50
HRH1 P35367 1/20 0.50
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
ALPL P05186 1/20 0.47
ALPG P10696 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
PSEN1 P49768 3/20 0.46
PSEN2 P49810 3/20 0.46
APH1B Q8WW43 3/20 0.46
NCSTN Q92542 3/20 0.46
APH1A Q96BI3 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14280389 0.90 PGR (0.46) PGRRORARORCRORBALDH1A1
SCHEMBL14280398 0.88 PGR (0.51) PGRRORARORCRORBALDH1A1
SCHEMBL29654225 0.87 RORA (0.62) PGRRORARORCRORBALDH1A1
SCHEMBL14493936 0.87 RORA (0.62) PGRRORARORCRORBALDH1A1
SCHEMBL10730998 0.84 PGR (0.70) PGRRORARORCRORBALDH1A1
SCHEMBL30213498 0.84 KDM4E (0.56) PGRRORARORCRORBALDH1A1
SCHEMBL12611201 0.84 KDM4E (0.56) PGRRORARORCRORBALDH1A1
SCHEMBL29717634 0.84 KDM4E (0.56) PGRRORARORCRORBALDH1A1
SCHEMBL14160792 0.84 PSEN1 (0.57) PGRRORARORCRORBALDH1A1
SCHEMBL14160794 0.83 TSPO (0.50) PGRRORARORCRORBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080020323-A1 Light sensitive planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2008-01-24 US disclosed
US-20080020323-A1 Light sensitive planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2008-01-24 US disclosed