Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | APP | P05067 | 3/20 | 0.58 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14280430 | 0.85 | MAPT (0.65) | MAPTAPPCTSLCTSBMEN1 | |
| SCHEMBL13672216 | 0.79 | MAPT (0.71) | MAPTAPPMEN1LMNAKMT2A | |
| Iodide SCHEMBL6670545 | 0.78 | MAPT (0.66) | MAPTAPPCTSLCTSBMEN1 | |
| Iodide SCHEMBL6673118 | 0.77 | MAPT (0.63) | MAPTAPPCTSLCTSBMEN1 | |
| Iodide SCHEMBL6673113 | 0.77 | MAPT (0.63) | MAPTAPPCTSLCTSBMEN1 | |
| SCHEMBL13235687 | 0.75 | MAPT (1.00) | MAPTAPPMEN1LMNAKMT2A | |
| SCHEMBL14156349 | 0.74 | MAPT (0.60) | MAPTAPPMEN1LMNAKMT2A | |
| SCHEMBL14280431 | 0.73 | MAPT (0.61) | MAPTAPPMEN1LMNAKMT2A | |
| Iodide SCHEMBL28572938 | 0.73 | MAPT (0.98) | MAPTAPPMEN1LMNAKMT2A | |
| Iodide SCHEMBL28579441 | 0.73 | MAPT (0.98) | MAPTAPPMEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7316890-B2 | Indolestyryl compound for use in recording media and method for fabrication thereof | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2008-01-08 | — | — | US | disclosed |