Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | APP | P05067 | 2/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 8/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14280437 | 0.88 | MAPT (0.49) | MAPTAPPPRMT1ACHEPRMT5 | |
| SCHEMBL13672219 | 0.85 | MAPT (0.51) | MAPTAPPPRMT1ACHEPRMT5 | |
| SCHEMBL14280434 | 0.85 | MAPT (0.40) | MAPTAPPPRMT1ACHECTSL | |
| SCHEMBL14280430 | 0.84 | MAPT (0.65) | MAPTAPPCTSLCTSBMEN1 | |
| SCHEMBL14280435 | 0.83 | MAPT (0.40) | MAPTAPPPRMT1PRMT5PRMT8 | |
| SCHEMBL14280431 | 0.77 | MAPT (0.61) | MAPTAPPPRMT1ACHEMEN1 | |
| SCHEMBL14280421 | 0.77 | MAPT (0.51) | MAPTAPPCTSLCTSBALDH1A1 | |
| SCHEMBL24437443 | 0.72 | DRD2 (0.51) | MAPTAPPPRMT1ACHEPRMT5 | |
| Iodide SCHEMBL6673113 | 0.72 | MAPT (0.63) | MAPTAPPPRMT1ACHECTSL | |
| Iodide SCHEMBL6673118 | 0.72 | MAPT (0.63) | MAPTAPPPRMT1ACHECTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7316890-B2 | Indolestyryl compound for use in recording media and method for fabrication thereof | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2008-01-08 | — | — | US | disclosed |