SCHEMBL14280606

SCHEMBL14280606

COCCOCCOCC(COCC(COc1ccc(CI)cc1)(COc1ccc(CI)cc1)COc1ccc(CI)cc1)(COc1ccc(CI)cc1)COc1ccc(CI)cc1

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
RECQL P46063 1/20 0.36
APP P05067 7/20 0.35
MEN1 O00255 1/20 0.31
USP2 O75604 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPK1 P28482 1/20 0.31
CASP1 P29466 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
SLCO1B3 Q9NPD5 1/20 0.31
SLCO1B1 Q9Y6L6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14280611 0.98 KDM4E (0.37) KDM4ERECQLAPPMEN1USP2
SCHEMBL14280633 0.92 APP (0.33) KDM4EAPPMEN1USP2ALDH1A1
SCHEMBL14280632 0.91 APP (0.34) KDM4EAPPMEN1USP2ALDH1A1
SCHEMBL14280642 0.82 APP (0.38) KDM4EAPPMEN1USP2ALDH1A1
SCHEMBL14280616 0.82 KDM4E (0.50) KDM4ERECQLAPPMEN1USP2
SCHEMBL14838239 0.80 DRD2 (0.40) KDM4ERECQLLMNAKMT2A
SCHEMBL14280603 0.77 ACACB (0.42) KDM4ERECQLAPP
SCHEMBL16021744 0.76 KMT2A (0.40) KDM4ERECQLMEN1ALDH1A1LMNA
SCHEMBL14280638 0.74 KCNH2 (0.32)
SCHEMBL14280618 0.73 APP (0.47) KDM4ERECQLAPPMEN1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080021185-A1 initiator systems; block polymers of vinyl acetate, vinyl alcohol, or polyvinyl butyral; use as water-soluble films, biodegradable and water-soluble polymers, detergents, in adhesives and as emulsifier; e.g. star polyethylene glycol modified with polyvinyl alcohol groups through a phenylene spacer CELANESE VENTURES GMBH (DE) 2008-01-24 US disclosed
US-20080021185-A1 initiator systems; block polymers of vinyl acetate, vinyl alcohol, or polyvinyl butyral; use as water-soluble films, biodegradable and water-soluble polymers, detergents, in adhesives and as emulsifier; e.g. star polyethylene glycol modified with polyvinyl alcohol groups through a phenylene spacer CELANESE VENTURES GMBH (DE) 2008-01-24 US disclosed