Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.40 |
| ▸ | DRD4 | P21917 | 6/20 | 0.40 |
| ▸ | DRD3 | P35462 | 6/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15025997 | 0.83 | DRD2 (0.47) | DRD2DRD4DRD3L3MBTL1ACHE | |
| SCHEMBL16021744 | 0.82 | KMT2A (0.40) | L3MBTL1NPC1KDM4ERECQLRAB9A | |
| SCHEMBL14280611 | 0.81 | KDM4E (0.37) | KDM4ERECQLKMT2ALMNA | |
| SCHEMBL14280606 | 0.80 | KDM4E (0.36) | KDM4ERECQLKMT2ALMNA | |
| SCHEMBL10042114 | 0.80 | KDM4E (0.54) | DRD2DRD4DRD3L3MBTL1ACHE | |
| SCHEMBL20234188 | 0.80 | KDM4E (0.54) | DRD2DRD4DRD3L3MBTL1ACHE | |
| SCHEMBL13645868 | 0.80 | DRD2 (0.46) | DRD2DRD4DRD3L3MBTL1ACHE | |
| SCHEMBL21897674 | 0.80 | KDM4E (0.54) | DRD2DRD4DRD3L3MBTL1ACHE | |
| SCHEMBL15585749 | 0.80 | KDM4E (0.54) | DRD2DRD4DRD3L3MBTL1ACHE | |
| SCHEMBL12835053 | 0.80 | KDM4E (0.54) | DRD2DRD4DRD3L3MBTL1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160083398-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2016-03-24 | — | — | US | disclosed |
| US-9227986-B2 | Diarylethene compounds and uses thereof | SWITCH MATERIALS, INC. (CA) | 2016-01-05 | — | — | US | disclosed |
| US-20150036204-A1 | OPTICAL FILTER WITH LIGHT SOURCE | SWITCH MATERIALS, INC. (CA) | 2015-02-05 | — | — | US | disclosed |
| US-20140256936-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2014-09-11 | — | — | US | disclosed |
| WO-2013123592-A1 | OPTICAL FILTER WITH LIGHT SOURCE | SWITCH MATERIALS INC. (CA) | 2013-08-29 | — | — | WO | disclosed |
| WO-2013106921-A1 | COMPOSITE OPTICAL FILTER | SWITCH MATERIALS , INC. (CA) | 2013-07-25 | — | — | WO | disclosed |
| WO-2013044371-A1 | PHOTOCHROMIC AND ELECTROCHROMIC DIARYLCYCLOPENTENE DERIVATIVES AS OPTICAL FILTERS | SWITCH MATERIALS, INC. (CA) | 2013-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256936-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | KCNH2, KCNH3, SCN2B | DRD2 417/4885DRD4 486/4885DRD3 665/4885 |
| US-20160083398-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | KCNH2, KCNH3, SCN2B | DRD2 417/4885DRD4 486/4885DRD3 665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.