Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CCR2 | P41597 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | CCR1 | P32246 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GGT1 | P19440 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4020292 | 0.87 | LMNA (0.59) | HTTCCR2ALDH1A1HPGDKDM4E | |
| SCHEMBL30775029 | 0.87 | LMNA (0.59) | HTTCCR2ALDH1A1HPGDKDM4E | |
| SCHEMBL4142669 | 0.85 | CTNNB1 (0.67) | HTTKMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL30775031 | 0.85 | CTNNB1 (0.67) | HTTKMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL2778881 | 0.84 | MAPT (0.61) | HTTKMT2ACCR2ALDH1A1HPGD | |
| SCHEMBL29842430 | 0.84 | MAPT (0.61) | HTTKMT2ACCR2ALDH1A1HPGD | |
| SCHEMBL11483350 | 0.83 | EPAS1 (0.53) | CCR2ALDH1A1HPGDKDM4ETSHR | |
| SCHEMBL1798 | 0.81 | CTNNB1 (0.71) | HTTKMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL28411450 | 0.81 | CTNNB1 (0.66) | HTTKMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL10421185 | 0.81 | ALDH1A1 (0.54) | HTTKMT2AALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118546106-A | Phenoxy benzamide derivative containing substituted oxadiazole, preparation method and application thereof | 宁夏大学 | 2024-08-27 | — | — | CN | disclosed |
| CN-117164517-A | Phenoxybenzamide derivative containing substituted pyrazole, preparation method and application thereof | 西北农林科技大学 | 2023-12-05 | — | — | CN | disclosed |
| US-20080021085-A1 | METHOD OF REDUCING ABETA42 AND TREATING DISEASES | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2008-01-24 | — | — | US | disclosed |
| US-20080021085-A1 | METHOD OF REDUCING ABETA42 AND TREATING DISEASES | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2008-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080021085-A1 | METHOD OF REDUCING ABETA42 AND TREATING DISEASES | BACE1, BACE2, APP | HTT 26/4885KMT2A 1301/4885CCR2 3557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.