SCHEMBL14280773

SCHEMBL14280773

CCc1cccc(CC)c1/N=C(\C)c1cccc(/C(C)=N/c2c(C)cccc2C)n1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.39
GABRA1 P14867 4/20 0.38
GABRB2 P47870 4/20 0.38
PKM P14618 1/20 0.36
GRIN2D O15399 2/20 0.34
GRIN3B O60391 2/20 0.34
GRIN1 Q05586 2/20 0.34
GRIN2A Q12879 2/20 0.34
GRIN2B Q13224 2/20 0.34
GRIN2C Q14957 2/20 0.34
GRIN3A Q8TCU5 2/20 0.34
SIGMAR1 Q99720 2/20 0.34
ELANE P08246 1/20 0.34
LMNA P02545 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
MAPT P10636 2/20 0.33
HSP90AA1 P07900 1/20 0.32
KDM4E B2RXH2 3/20 0.32
ALOX15 P16050 2/20 0.32
TSHR P16473 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4883854 0.92 GABRA1 (0.43) CYP1A2GABRA1GABRB2ELANELMNA
SCHEMBL4883849 0.92 GABRA1 (0.43) CYP1A2GABRA1GABRB2ELANELMNA
SCHEMBL5590407 0.91 GABRA1 (0.42) CYP1A2GABRA1GABRB2ELANELMNA
Hydrochloric Acid SCHEMBL7175505 0.91 GABRA1 (0.42) CYP1A2GABRA1GABRB2ELANELMNA
SCHEMBL14280782 0.90 CYP1A2 (0.36) CYP1A2GABRA1GABRB2SIGMAR1ELANE
Hydrochloric Acid SCHEMBL7179429 0.89 GABRA1 (0.41) CYP1A2GABRA1GABRB2ELANELMNA
Hydrochloric Acid SCHEMBL7183844 0.89 GABRA1 (0.41) CYP1A2GABRA1GABRB2ELANELMNA
Hydrochloric Acid SCHEMBL7171333 0.89 GABRA1 (0.41) CYP1A2GABRA1GABRB2ELANELMNA
Hydrochloric Acid SCHEMBL7177025 0.89 GABRA1 (0.41) CYP1A2GABRA1GABRB2ELANELMNA
Hydrochloric Acid SCHEMBL7178859 0.89 GABRA1 (0.41) CYP1A2GABRA1GABRB2ELANELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080021180-A1 CHROMIUM CATALYSTS ACTIVE IN OLEFIN POLYMERIZATION REPSOL QUIMICA, S.A. 2008-01-24 US disclosed
US-20080021180-A1 CHROMIUM CATALYSTS ACTIVE IN OLEFIN POLYMERIZATION REPSOL QUIMICA, S.A. 2008-01-24 US disclosed