Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4527151 | 0.92 | CYP1A2 (0.33) | CYP1A2GABRA1GABRB2LMNASMN1; SMN2 | |
| SCHEMBL4527146 | 0.92 | CYP1A2 (0.33) | CYP1A2GABRA1GABRB2LMNASMN1; SMN2 | |
| SCHEMBL14280780 | 0.91 | SIGMAR1 (0.38) | CYP1A2GABRA1GABRB2LMNASMN1; SMN2 | |
| SCHEMBL14280773 | 0.90 | CYP1A2 (0.39) | CYP1A2GABRA1GABRB2LMNASMN1; SMN2 | |
| SCHEMBL14280819 | 0.88 | GABRA1 (0.39) | CYP1A2GABRA1GABRB2LMNASMN1; SMN2 | |
| SCHEMBL14280772 | 0.88 | CYP1A2 (0.40) | CYP1A2GABRA1GABRB2LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7175041 | 0.88 | PAX8 (0.35) | CYP1A2LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL4883849 | 0.88 | GABRA1 (0.43) | CYP1A2GABRA1GABRB2LMNASMN1; SMN2 | |
| SCHEMBL453477 | 0.88 | HSP90AA1 (0.36) | CYP1A2KMT2AMEN1ALDH1A1SIGMAR1 | |
| SCHEMBL4883854 | 0.88 | GABRA1 (0.43) | CYP1A2GABRA1GABRB2LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080021180-A1 | CHROMIUM CATALYSTS ACTIVE IN OLEFIN POLYMERIZATION | REPSOL QUIMICA, S.A. | 2008-01-24 | — | — | US | disclosed |
| US-20080021180-A1 | CHROMIUM CATALYSTS ACTIVE IN OLEFIN POLYMERIZATION | REPSOL QUIMICA, S.A. | 2008-01-24 | — | — | US | disclosed |