Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14280791 | 0.86 | CYP1A2 (0.44) | CYP1A2CYP2A6THRBPAX8MEN1 | |
| SCHEMBL453477 | 0.86 | HSP90AA1 (0.36) | SIGMAR1CYP1A2CYP2A6PAX8GRIN2D | |
| SCHEMBL453478 | 0.86 | HSP90AA1 (0.36) | SIGMAR1CYP1A2CYP2A6PAX8GRIN2D | |
| SCHEMBL5358995 | 0.86 | SIGMAR1 (0.46) | SIGMAR1CYP1A2F2PLGCYP3A4 | |
| SCHEMBL5354574 | 0.86 | SIGMAR1 (0.46) | SIGMAR1CYP1A2F2PLGCYP3A4 | |
| SCHEMBL5587833 | 0.84 | HSP90AA1 (0.35) | SIGMAR1CYP1A2CYP2A6PAX8GRIN2D | |
| SCHEMBL5587427 | 0.84 | HSP90AA1 (0.35) | SIGMAR1CYP1A2CYP2A6PAX8GRIN2D | |
| SCHEMBL5588611 | 0.84 | HSP90AA1 (0.35) | SIGMAR1CYP1A2CYP2A6PAX8GRIN2D | |
| SCHEMBL5588127 | 0.84 | HSP90AA1 (0.35) | SIGMAR1CYP1A2CYP2A6PAX8GRIN2D | |
| SCHEMBL5588774 | 0.84 | HSP90AA1 (0.35) | SIGMAR1CYP1A2CYP2A6PAX8GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080021180-A1 | CHROMIUM CATALYSTS ACTIVE IN OLEFIN POLYMERIZATION | REPSOL QUIMICA, S.A. | 2008-01-24 | — | — | US | disclosed |
| US-20080021180-A1 | CHROMIUM CATALYSTS ACTIVE IN OLEFIN POLYMERIZATION | REPSOL QUIMICA, S.A. | 2008-01-24 | — | — | US | disclosed |