Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.35 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14280784 | 0.90 | CYP1A2 (0.38) | CYP1A2ALDH1A1HPGDHSD17B10PAX8 | |
| SCHEMBL453478 | 0.88 | HSP90AA1 (0.36) | CYP1A2CYP2A6ALDH1A1HSD17B10PAX8 | |
| SCHEMBL453477 | 0.88 | HSP90AA1 (0.36) | CYP1A2CYP2A6ALDH1A1HSD17B10PAX8 | |
| SCHEMBL5588127 | 0.87 | HSP90AA1 (0.35) | CYP1A2CYP2A6ALDH1A1HSD17B10PAX8 | |
| SCHEMBL5587833 | 0.87 | HSP90AA1 (0.35) | CYP1A2CYP2A6ALDH1A1HSD17B10PAX8 | |
| SCHEMBL5590270 | 0.87 | HSP90AA1 (0.35) | CYP1A2CYP2A6ALDH1A1HSD17B10PAX8 | |
| SCHEMBL5588611 | 0.87 | HSP90AA1 (0.35) | CYP1A2CYP2A6ALDH1A1HSD17B10PAX8 | |
| SCHEMBL5588774 | 0.87 | HSP90AA1 (0.35) | CYP1A2CYP2A6ALDH1A1HSD17B10PAX8 | |
| SCHEMBL5587427 | 0.87 | HSP90AA1 (0.35) | CYP1A2CYP2A6ALDH1A1HSD17B10PAX8 | |
| SCHEMBL14280783 | 0.86 | SIGMAR1 (0.42) | CYP1A2CYP2A6THRBPAX8MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080021180-A1 | CHROMIUM CATALYSTS ACTIVE IN OLEFIN POLYMERIZATION | REPSOL QUIMICA, S.A. | 2008-01-24 | — | — | US | disclosed |
| US-20080021180-A1 | CHROMIUM CATALYSTS ACTIVE IN OLEFIN POLYMERIZATION | REPSOL QUIMICA, S.A. | 2008-01-24 | — | — | US | disclosed |