Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21836279 | 0.82 | KDM4E (0.58) | KDM4ETDP1LMNASMN1; SMN2MITF | |
| SCHEMBL21836280 | 0.82 | KDM4E (0.58) | KDM4ETDP1LMNASMN1; SMN2MITF | |
| SCHEMBL6916470 | 0.76 | KDM4E (0.38) | NOS2KDM4EALOX15TSHRACMSD | |
| SCHEMBL6916473 | 0.76 | KDM4E (0.38) | NOS2KDM4EALOX15TSHRACMSD | |
| SCHEMBL21836259 | 0.76 | LMNA (0.44) | NOS2TDP1LMNASMN1; SMN2NOS3 | |
| SCHEMBL21836260 | 0.76 | LMNA (0.44) | NOS2TDP1LMNASMN1; SMN2NOS3 | |
| SCHEMBL21836222 | 0.74 | NR4A1 (0.46) | POLBMEN1NPC1RAB9AKMT2A | |
| SCHEMBL21836225 | 0.74 | NR4A1 (0.46) | POLBMEN1NPC1RAB9AKMT2A | |
| SCHEMBL11525479 | 0.73 | NOS2 (0.47) | NOS2KDM4ETDP1LMNANOS3 | |
| Hydrochloric Acid SCHEMBL7180440 | 0.73 | KDM4E (0.37) | KDM4EALOX15TSHRACMSDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080021180-A1 | CHROMIUM CATALYSTS ACTIVE IN OLEFIN POLYMERIZATION | REPSOL QUIMICA, S.A. | 2008-01-24 | — | — | US | disclosed |
| US-20080021180-A1 | CHROMIUM CATALYSTS ACTIVE IN OLEFIN POLYMERIZATION | REPSOL QUIMICA, S.A. | 2008-01-24 | — | — | US | disclosed |