SCHEMBL14280799

SCHEMBL14280799

Cc1cccc(C)c1/N=C(\c1ccccc1)c1cccc(/C(=N/c2c(C)cccc2C)c2ccccc2)n1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 2/20 0.39
GRIN3B O60391 2/20 0.39
GRIN1 Q05586 2/20 0.39
GRIN2A Q12879 2/20 0.39
GRIN2B Q13224 2/20 0.39
GRIN2C Q14957 2/20 0.39
GRIN3A Q8TCU5 2/20 0.39
SIGMAR1 Q99720 2/20 0.39
ALDH1A1 P00352 6/20 0.38
LMNA P02545 1/20 0.38
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
AGTR1 P30556 1/20 0.36
KDM4E B2RXH2 1/20 0.35
ALOX15 P16050 1/20 0.35
TSHR P16473 1/20 0.35
ACMSD Q8TDX5 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5590682 1.00 GRIN2D (0.39) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL5586966 0.98 GRIN2D (0.38) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL25647094 0.91 LCK (0.36) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL23975016 0.89 ALDH1A1 (0.36) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL21078306 0.89 LCK (0.37) ALDH1A1LMNAHTTSMN1; SMN2ESR1
SCHEMBL14280811 0.89 ALDH1A1 (0.39) ALDH1A1LMNAHTTSMN1; SMN2ESR1
SCHEMBL5589752 0.89 ALDH1A1 (0.39) ALDH1A1LMNAHTTSMN1; SMN2ESR1
SCHEMBL5589661 0.87 ALDH1A1 (0.38) ALDH1A1LMNAHTTSMN1; SMN2ESR1
SCHEMBL5588460 0.87 LMNA (0.39) ALDH1A1LMNAHTTSMN1; SMN2ESR1
SCHEMBL16077925 0.86 ALDH1A1 (0.38) ALDH1A1LMNAHTTSMN1; SMN2AGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9695260-B2 Method for producing olefin block polymer using plurality of types of transition metal catalysts SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-04 US disclosed
US-20140275429-A1 METHOD FOR PRODUCING OLEFIN BLOCK POLYMER USING PLURALITY OF TYPES OF TRANSITION METAL CATALYSTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-09-18 US disclosed
US-20080021180-A1 CHROMIUM CATALYSTS ACTIVE IN OLEFIN POLYMERIZATION REPSOL QUIMICA, S.A. 2008-01-24 US disclosed
US-20080021180-A1 CHROMIUM CATALYSTS ACTIVE IN OLEFIN POLYMERIZATION REPSOL QUIMICA, S.A. 2008-01-24 US disclosed