Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 3/20 | 0.56 |
| ▸ | ESR1 | P03372 | 2/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EBP | Q15125 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5588070 | 1.00 | ESR2 (0.56) | ESR2ESR1SIGMAR1GAAGRIN2D | |
| SCHEMBL5588553 | 0.98 | ESR2 (0.54) | ESR2ESR1SIGMAR1GAAGRIN2D | |
| SCHEMBL19891840 | 0.85 | ESR2 (0.51) | ESR2ESR1GAAMEN1KMT2A | |
| SCHEMBL5590682 | 0.85 | GRIN2D (0.39) | ESR2ESR1SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL14280799 | 0.85 | GRIN2D (0.39) | ESR2ESR1SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL5587353 | 0.84 | KMT2A (0.41) | ESR2ESR1GAAALOX15TSHR | |
| SCHEMBL19887500 | 0.84 | KMT2A (0.41) | ESR2ESR1GAAALOX15TSHR | |
| SCHEMBL19844907 | 0.84 | ESR2 (0.53) | ESR2ESR1GAAMEN1KMT2A | |
| SCHEMBL15275530 | 0.84 | ESR2 (0.75) | ESR2ESR1SIGMAR1GAAGRIN2D | |
| SCHEMBL5586966 | 0.83 | GRIN2D (0.38) | ESR2ESR1SIGMAR1GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180051103-A1 | OLIGOMER PRODUCTION METHOD AND CATALYST | JXTG NIPPON OIL & ENERGY CORPORATION (JP) | 2018-02-22 | — | — | US | disclosed |
| US-20180051103-A1 | OLIGOMER PRODUCTION METHOD AND CATALYST | JXTG NIPPON OIL & ENERGY CORPORATION (JP) | 2018-02-22 | — | — | US | disclosed |
| US-20080021180-A1 | CHROMIUM CATALYSTS ACTIVE IN OLEFIN POLYMERIZATION | REPSOL QUIMICA, S.A. | 2008-01-24 | — | — | US | disclosed |
| US-20080021180-A1 | CHROMIUM CATALYSTS ACTIVE IN OLEFIN POLYMERIZATION | REPSOL QUIMICA, S.A. | 2008-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180051103-A1 | OLIGOMER PRODUCTION METHOD AND CATALYST | OR51E2, NOD2, MSMO1 | ESR2 853/4885ESR1 389/4885SIGMAR1 2183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.