Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.40 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL207231 | 0.88 | ERN1 (0.50) | ERN1LMNAALDH1A1CYP1A1CYP1B1 | |
| 2,4,6-Trimethoxybenzaldehyde SCHEMBL34873 | 0.86 | ERN1 (0.74) | ERN1LMNAALDH1A1ABCG2CYP1A1 | |
| 2,4,6-Trimethoxybenzaldehyde SCHEMBL28687257 | 0.84 | ERN1 (0.71) | ERN1LMNAALDH1A1ABCG2CYP1A1 | |
| SCHEMBL5623138 | 0.83 | ERN1 (0.71) | ERN1LMNAALDH1A1ABCG2CYP3A4 | |
| SCHEMBL1251300 | 0.82 | ERN1 (0.53) | ERN1LMNAALDH1A1CYP1A2PRKDC | |
| 2,4,6-Trimethoxybenzaldehyde SCHEMBL28687256 | 0.82 | ERN1 (0.75) | ERN1LMNAALDH1A1ABCG2CYP1A1 | |
| SCHEMBL28243418 | 0.81 | ERN1 (0.44) | ERN1LMNAALDH1A1ABCG2CYP1A1 | |
| SCHEMBL23783406 | 0.79 | ERN1 (0.50) | ERN1LMNAALDH1A1CYP1A2PRKDC | |
| SCHEMBL1459113 | 0.79 | ERN1 (0.43) | ERN1LMNAALDH1A1CYP1A1CYP1B1 | |
| SCHEMBL30230047 | 0.78 | ERN1 (0.65) | ERN1LMNAALDH1A1ABCG2CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720038-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246496-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2024-12-05 | — | — | WO | disclosed |
| EP-2970339-B1 | 1-HYDROXY-BENZOOXABOROLES AS ANTIPARASITIC AGENTS | LILLY CO ELI (US) | 2017-08-16 | — | — | EP | disclosed |
| US-9617285-B2 | 1-hydroxy-benzooxaboroles as antiparasitic agents | ELI LILLY AND COMPANY (US) | 2017-04-11 | — | — | US | disclosed |
| CN-105051048-B | 1-hydroxy-benzoxaboroles as antiparasitic agents | 伊莱利利公司 | 2017-03-15 | — | — | CN | disclosed |
| EP-2970339-A1 | 1 -HYDROXY-BENZOOXABOROLES AS ANTIPARASITIC AGENTS | Eli Lilly and Company (US) | 2016-01-20 | — | — | EP | disclosed |
| US-9216980-B2 | Methods of use of diazacarbazoles for treating cancer | GENENTECH, INC. (US) | 2015-12-22 | — | — | US | disclosed |
| US-20150353581-A1 | 1-HYDROXY-BENZOOXABOROLES AS ANTIPARASITIC AGENTS | ELI LILLY AND COMPANY (US) | 2015-12-10 | — | — | US | disclosed |
| CN-105051048-A | 1-hydroxy-benzoxaboroles as antiparasitic agents | LILLY CO ELI | 2015-11-11 | — | — | CN | disclosed |
| US-20150087630-A1 | METHODS OF USE OF DIAZACARBAZOLES FOR TREATING CANCER | GENENTECH, INC. (US) | 2015-03-26 | — | — | US | disclosed |
| US-20090023779-A1 | Indazoles, benzisoxazoles and benzisothiazoles and their use as estrogenic agents | LABORATOIRE THERAMEX (FR) | 2009-01-22 | — | — | US | disclosed |
| CN-101080395-A | Indazoles, benzisoxazoles and benzisothiazoles and their use as estrogenic agents | THERAMEX (MC) | 2007-11-28 | — | — | CN | disclosed |
| EP-1812404-A1 | INDAZOLES, BENZISOXAZOLES AND BENZISOTHIAZOLES AND THEIR USE AS ESTROGENIC AGENTS | LABORATOIRE THERAMEX (MC) | 2007-08-01 | — | — | EP | disclosed |
| US-7226945-B2 | Estrogen receptor-β ligands | ASTRAZENECA AB (SE) | 2007-06-05 | — | — | US | disclosed |
| WO-2006040351-A1 | INDAZOLES, BENZISOXAZOLES AND BENZISOTHIAZOLES AND THEIR USE AS ESTROGENIC AGENTS | LABORATOIRE THERAMEX (MC) | 2006-04-20 | — | — | WO | disclosed |
| EP-1647549-A1 | Indazoles, benzisoxazoles and benzisothiazoles as estrogenic agents | LABORATOIRE THERAMEX (MC) | 2006-04-19 | — | — | EP | disclosed |
| US-20050043350-A9 | Estrogen Receptor-beta ligands | ASTRAZENECA AB (SE) | 2005-02-24 | — | — | US | disclosed |
| US-20040039015-A1 | Estrogen Receptor-beta ligands | BARLAAM BERNARD (FR) | 2004-02-26 | — | — | US | disclosed |
| EP-1326593-A1 | ESTROGEN RECEPTOR-$g(b) LIGANDS | AstraZeneca AB (SE) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002030407-A1 | ESTROGEN RECEPTOR-β LIGANDS | ASTRAZENECA AB (SE) | 2002-04-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043350-A9 | Estrogen Receptor-beta ligands | ESR2, GPER1, ESR1 | ERN1 1985/4885LMNA 4303/4885ALDH1A1 1519/4885 |
| US-20090023779-A1 | Indazoles, benzisoxazoles and benzisothiazoles and their use as estrogenic agents | ESR1, ESR2, GPER1 | ERN1 1233/4885LMNA 3061/4885ALDH1A1 570/4885 |
| US-20150353581-A1 | 1-HYDROXY-BENZOOXABOROLES AS ANTIPARASITIC AGENTS | HAO1, CYP8B1, KMO | ERN1 3051/4885LMNA 4151/4885ALDH1A1 518/4885 |
| US-20040039015-A1 | Estrogen Receptor-beta ligands | ESR2, GPER1, ESRRG | ERN1 1552/4885LMNA 4363/4885ALDH1A1 1336/4885 |
| US-20150087630-A1 | METHODS OF USE OF DIAZACARBAZOLES FOR TREATING CANCER | IDH3B, IDH3A, EGLN3 | ERN1 4440/4885LMNA 2307/4885ALDH1A1 220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.