Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 2/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PLG | P00747 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.31 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1975176 | 0.82 | CSNK2A2 (0.36) | SMN1; SMN2CSNK2A2CSNK2A1 | |
| SCHEMBL28722096 | 0.80 | CSNK2A2 (0.37) | DPP4CSNK2A2CSNK2A1OPRK1 | |
| SCHEMBL17076623 | 0.79 | ALOX5 (0.35) | CSNK2A2CSNK2A1LMNAHSD17B10CHRM3 | |
| SCHEMBL28722121 | 0.77 | CSNK2A2 (0.35) | CSNK2A2CSNK2A1 | |
| SCHEMBL1711675 | 0.72 | CPN1 (0.35) | DPP4CSNK2A2CSNK2A1LMNAHSD17B10 | |
| SCHEMBL1430764 | 0.71 | GNAI3 (0.41) | GNAI3GNAO1GNAI1SMN1; SMN2DPP4 | |
| SCHEMBL16338060 | 0.70 | ALOX5 (0.33) | DPP4CSNK2A2CSNK2A1 | |
| SCHEMBL561977 | 0.70 | CSNK2A2 (0.31) | CSNK2A2CSNK2A1 | |
| SCHEMBL16338061 | 0.70 | ALOX5 (0.33) | DPP4CSNK2A2CSNK2A1 | |
| SCHEMBL561979 | 0.70 | CSNK2A2 (0.31) | CSNK2A2CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300007-A1 | N-PIPERIDINYL ACETAMIDE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | Zalicus Pharmaceuticals Ltd. (CA) | 2011-03-30 | — | — | EP | disclosed |