Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CCR2 | P41597 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | XPO1 | O14980 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2807104 | 0.83 | ALDH1A1 (0.58) | ALDH1A1MAPTKDM4ETDP1ALOX15 | |
| Hydrochloric Acid SCHEMBL10734951 | 0.83 | MEN1 (0.53) | PPARGPPARATDP1CCR2MEN1 | |
| SCHEMBL2930491 | 0.83 | CCR2 (0.51) | ALDH1A1PPARGPPARAMAPTKDM4E | |
| SCHEMBL1760912 | 0.82 | CCR2 (0.50) | ALDH1A1PPARGPPARAMAPTCCR2 | |
| SCHEMBL187309 | 0.81 | MEN1 (0.50) | ALDH1A1PPARGPPARAMAPTTDP1 | |
| SCHEMBL10738116 | 0.79 | CCR2 (0.52) | ALDH1A1MAPTKDM4ECCR2ALOX15 | |
| SCHEMBL10972353 | 0.79 | PPARG (0.52) | PPARGPPARAMAPTKDM4ECCR2 | |
| SCHEMBL1274660 | 0.78 | PDK4 (0.51) | ALDH1A1MAPTKDM4ETDP1GRM5 | |
| Hydrochloric Acid SCHEMBL10736189 | 0.78 | PPARG (0.51) | PPARGPPARAMAPTKDM4ECCR2 | |
| SCHEMBL10638336 | 0.78 | HTR2C (0.54) | PPARGPPARAHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080015225-A1 | Dimeric Piperidine Derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-01-17 | — | — | US | disclosed |
| US-20080015225-A1 | Dimeric Piperidine Derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080015225-A1 | Dimeric Piperidine Derivatives | PTGER4, PTGER3, PTGER1 | ALDH1A1 646/4885PPARG 810/4885PPARA 614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.