Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4404861 | 0.79 | IDO1 (0.57) | MAPTLMNAMEN1KMT2AIDO1 | |
| SCHEMBL26185832 | 0.78 | MAOB (0.58) | MAPTLMNAMEN1KMT2AIDO1 | |
| SCHEMBL14282997 | 0.77 | SMN1; SMN2 (0.48) | MAPTLMNAMEN1KMT2APOLB | |
| SCHEMBL22498332 | 0.77 | HTT (0.38) | LMNAMEN1KMT2AIDO1CA12 | |
| SCHEMBL2504040 | 0.76 | ACP1 (0.36) | MAPTLMNAMEN1KMT2AIDO1 | |
| SCHEMBL22128468 | 0.75 | ALDH1A1 (0.40) | MAPTLMNAMEN1KMT2AIDO1 | |
| SCHEMBL15522365 | 0.75 | HTR2A (0.55) | MAPTIDO1POLBALDH1A1MAOB | |
| SCHEMBL17494979 | 0.73 | ALDH1A1 (0.36) | LMNAMEN1KMT2AIDO1POLB | |
| SCHEMBL18538981 | 0.72 | HTT (0.38) | MAPTLMNAMEN1KMT2AIDO1 | |
| SCHEMBL1879222 | 0.72 | TSHR (0.50) | MAPTLMNAMEN1KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8352193-B2 | Methods for deriving a cumulative ranking | TARGET DISCOVERY, INC. (US) | 2013-01-08 | — | — | US | disclosed |
| US-7316931-B2 | Mass defect labeling for the determination of oligomer sequences | TARGET DISCOVERY, INC. (US) | 2008-01-08 | — | — | US | disclosed |
| US-20070154900-A1 | Methods for determining protein and peptide terminal sequences | TARGET DISCOVERY, INC (US) | 2007-07-05 | — | — | US | disclosed |