Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30549649 | 0.78 | LMNA (0.43) | SMN1; SMN2LMNAGAAMAPTALDH1A1 | |
| SCHEMBL14282996 | 0.77 | MAPT (0.39) | SMN1; SMN2LMNAMAPTALDH1A1NPSR1 | |
| SCHEMBL22128468 | 0.76 | ALDH1A1 (0.40) | SMN1; SMN2LMNAGAAMAPTALDH1A1 | |
| SCHEMBL14282994 | 0.73 | MAOB (0.47) | SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL19405909 | 0.73 | GPR35 (0.43) | SMN1; SMN2LMNAMAPTALDH1A1HPGD | |
| SCHEMBL481257 | 0.73 | IDO1 (0.50) | SMN1; SMN2LMNAMAPTALDH1A1HPGD | |
| SCHEMBL18587538 | 0.73 | MAPT (0.48) | SMN1; SMN2LMNAMAPTALDH1A1NPSR1 | |
| SCHEMBL31320855 | 0.72 | ALDH1A1 (0.51) | SMN1; SMN2MAPTALDH1A1HPGDKMT2A | |
| SCHEMBL22264774 | 0.72 | ALDH1A1 (0.51) | SMN1; SMN2MAPTALDH1A1HPGDKMT2A | |
| SCHEMBL357298 | 0.72 | ALDH1A1 (0.42) | SMN1; SMN2LMNAGAAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8352193-B2 | Methods for deriving a cumulative ranking | TARGET DISCOVERY, INC. (US) | 2013-01-08 | — | — | US | disclosed |
| US-7316931-B2 | Mass defect labeling for the determination of oligomer sequences | TARGET DISCOVERY, INC. (US) | 2008-01-08 | — | — | US | disclosed |
| US-20070154900-A1 | Methods for determining protein and peptide terminal sequences | TARGET DISCOVERY, INC (US) | 2007-07-05 | — | — | US | disclosed |