Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4684362 | 0.91 | MEN1 (0.49) | MEN1KMT2ATHRBKDM4EALDH1A1 | |
| SCHEMBL6372652 | 0.89 | LMNA (0.55) | MEN1KMT2ATHRBKDM4EALDH1A1 | |
| SCHEMBL4699056 | 0.89 | MEN1 (0.47) | MEN1KMT2ATHRBKDM4EALDH1A1 | |
| SCHEMBL14458094 | 0.89 | MAOB (0.46) | MEN1KMT2ASMPD1HDAC1HDAC8 | |
| SCHEMBL14458101 | 0.86 | HPGD (0.48) | MEN1KMT2ATHRBKDM4EALDH1A1 | |
| SCHEMBL14458100 | 0.83 | PTPN1 (0.48) | MEN1KMT2ASMPD1HDAC1HDAC8 | |
| SCHEMBL14284319 | 0.83 | MEN1 (0.46) | MEN1KMT2ATHRBKDM4EALDH1A1 | |
| SCHEMBL6373978 | 0.82 | LMNA (0.56) | MEN1KMT2ATHRBALDH1A1MAPT | |
| SCHEMBL14284322 | 0.82 | MEN1 (0.47) | MEN1KMT2ATHRBKDM4EALDH1A1 | |
| SCHEMBL6373133 | 0.82 | THRA (0.47) | MEN1KMT2ATHRBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39991-E1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2008-01-01 | — | — | US | disclosed |