Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.49 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.41 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | USP36 | Q9P275 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12384673 | 0.79 | MAPT (0.57) | HPGDSNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL6055005 | 0.77 | ALDH1A1 (0.64) | HPGDSRAB9AALDH1A1HTTMAPT | |
| SCHEMBL13162007 | 0.76 | SIRT3 (0.53) | HPGDSNPC1RAB9AALDH1A1HTT | |
| SCHEMBL14284656 | 0.75 | KDM4E (0.44) | NPC1RAB9AALDH1A1HTTKDM4E | |
| SCHEMBL15651270 | 0.73 | SMYD3 (0.49) | HPGDSALDH1A1HTTKDM4EMAPT | |
| SCHEMBL3115088 | 0.73 | RAB9A (0.49) | ANO1NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL3108907 | 0.73 | RAB9A (0.49) | ANO1NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL3108915 | 0.73 | RAB9A (0.49) | ANO1NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL14082500 | 0.73 | CYP46A1 (0.57) | HPGDSNPC1RAB9AALDH1A1CYP46A1 | |
| SCHEMBL3122776 | 0.72 | RAB9A (0.43) | HPGDSRAB9AALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39991-E1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2008-01-01 | — | — | US | disclosed |
| US-RE39991-E1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2008-01-01 | — | — | US | disclosed |