Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.49 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.47 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | BRAF | P15056 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.45 |
| ▸ | USP36 | Q9P275 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14284648 | 0.89 | USP36 (0.49) | TLR8TLR7P2RX1NPC1RAB9A | |
| SCHEMBL14284658 | 0.89 | TLR8 (0.56) | TLR8TLR7RAB9AMAPTBRAF | |
| SCHEMBL14284646 | 0.83 | MAPT (0.44) | SMN1; SMN2MAPTPTGS1 | |
| SCHEMBL14284654 | 0.83 | PIN1 (0.45) | RAB9A | |
| SCHEMBL14284650 | 0.81 | GAA (0.49) | TLR8TLR7P2RX1P2RX4P2RX7 | |
| SCHEMBL14284358 | 0.81 | TLR7 (0.62) | TRPV1TLR7NPC1RAB9AMAPT | |
| SCHEMBL13503254 | 0.74 | TRPV1 (0.47) | TRPV1TLR8SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2237973 | 0.74 | MAPT (0.51) | TRPV1TLR8NPC1RAB9AMAPT | |
| SCHEMBL16586318 | 0.74 | AHR (0.50) | TRPV1TLR8TLR7SMN1; SMN2NPC1 | |
| SCHEMBL16585956 | 0.72 | MAPT (0.49) | TRPV1SMN1; SMN2NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39991-E1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2008-01-01 | — | — | US | disclosed |
| US-RE39991-E1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2008-01-01 | — | — | US | disclosed |