Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LIPE | Q05469 | 3/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14284653 | 0.89 | RXFP1 (0.49) | MAPTKDM4EMAPK1TSHRL3MBTL1 | |
| SCHEMBL14284668 | 0.83 | TRPV1 (0.49) | MAPTPTGS1SMN1; SMN2 | |
| SCHEMBL14284648 | 0.82 | USP36 (0.49) | MAPTRXFP1PTGS1LMNAMEN1 | |
| SCHEMBL14284654 | 0.80 | PIN1 (0.45) | L3MBTL1THRBLMNAMEN1KMT2A | |
| SCHEMBL14284658 | 0.75 | TLR8 (0.56) | MAPTKDM4EMAPK1TDP1L3MBTL1 | |
| SCHEMBL14284647 | 0.74 | PIN1 (0.46) | RXFP1THRB | |
| SCHEMBL14284650 | 0.74 | GAA (0.49) | MAPTKDM4EMAPK1TDP1L3MBTL1 | |
| SCHEMBL13265973 | 0.71 | RAB9A (0.74) | MAPTKDM4EMAPK1TSHRTDP1 | |
| SCHEMBL11429250 | 0.71 | RAB9A (0.63) | MAPTKDM4EMAPK1TSHRTDP1 | |
| SCHEMBL7126723 | 0.69 | PYGL (0.66) | MAPTKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39991-E1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2008-01-01 | — | — | US | disclosed |
| US-RE39991-E1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2008-01-01 | — | — | US | disclosed |