Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 6/20 | 0.36 |
| ▸ | PRKCA | P17252 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.33 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14535750 | 0.86 | BRD9 (0.32) | BRD9 | |
| SCHEMBL14285088 | 0.86 | TLR8 (0.41) | BRD9BRD4GSK3BPRKCAALDH1A1 | |
| SCHEMBL14285082 | 0.85 | NT5E (0.35) | CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL433808 | 0.76 | DYRK1A (0.49) | GSK3BKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17687649 | 0.70 | DYRK1A (0.42) | GSK3BKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14535751 | 0.64 | — | — | |
| SCHEMBL17681580 | 0.63 | GCGR (0.41) | CLK4DYRK1A | |
| SCHEMBL498496 | 0.62 | CYP1B1 (0.42) | GSK3BALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL28035340 | 0.61 | IDO1 (0.64) | BRD9BRD4GSK3BALDH1A1KDM4E | |
| SCHEMBL1680192 | 0.59 | ME2 (0.43) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7319147-B2 | Porphyrins and related compounds | BIOSCIENCE TECHNOLOGY INVESTMENT HOLDINGS LIMITED (MY) | 2008-01-15 | — | — | US | disclosed |
| US-7319147-B2 | Porphyrins and related compounds | BIOSCIENCE TECHNOLOGY INVESTMENT HOLDINGS LIMITED (MY) | 2008-01-15 | — | — | US | disclosed |