Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL357314 | 0.78 | MEN1 (0.64) | MEN1KMT2ARECQLTSHRKDM4E | |
| SCHEMBL3719179 | 0.78 | MEN1 (0.46) | MEN1KMT2ATSHRKDM4EALDH1A1 | |
| SCHEMBL12799428 | 0.78 | MEN1 (0.78) | MEN1KMT2ARECQLCYP1A2CYP2C9 | |
| SCHEMBL14285706 | 0.73 | CA2 (0.31) | — | |
| SCHEMBL13875921 | 0.72 | MCL1 (0.36) | KDM4E | |
| SCHEMBL14258481 | 0.71 | MEN1 (0.54) | MEN1KMT2ARECQLCYP1A2CYP2C9 | |
| SCHEMBL6754447 | 0.71 | MEN1 (0.54) | MEN1KMT2ARECQLCYP1A2CYP2C9 | |
| SCHEMBL19441962 | 0.70 | MEN1 (0.58) | MEN1KMT2ARECQLCYP1A2CYP2C9 | |
| SCHEMBL14197498 | 0.70 | MEN1 (0.58) | MEN1KMT2ARECQL | |
| SCHEMBL15934269 | 0.70 | MEN1 (0.73) | MEN1KMT2ARECQLTSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080020942-A1 | Reagents and Methods for Appending Functional Groups to Proteins | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080020942-A1 | Reagents and Methods for Appending Functional Groups to Proteins | PTMS, MTPN, FGB | MEN1 3264/4885KMT2A 4171/4885RECQL 2107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.