Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 12/20 | 0.71 |
| ▸ | BCR | P11274 | 8/20 | 0.71 |
| ▸ | KIT | P10721 | 8/20 | 0.71 |
| ▸ | LYN | P07948 | 6/20 | 0.71 |
| ▸ | CSF1R | P07333 | 6/20 | 0.71 |
| ▸ | BRAF | P15056 | 4/20 | 0.71 |
| ▸ | LCK | P06239 | 3/20 | 0.71 |
| ▸ | EGFR | P00533 | 3/20 | 0.71 |
| ▸ | ABL2 | P42684 | 3/20 | 0.71 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.71 |
| ▸ | FYN | P06241 | 2/20 | 0.71 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.71 |
| ▸ | FGR | P09769 | 2/20 | 0.71 |
| ▸ | SRC | P12931 | 2/20 | 0.71 |
| ▸ | NQO2 | P16083 | 2/20 | 0.71 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.71 |
| ▸ | EPHA8 | P29322 | 2/20 | 0.71 |
| ▸ | FRK | P42685 | 2/20 | 0.71 |
| ▸ | BLK | P51451 | 2/20 | 0.71 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6431039 | 0.93 | ABL1 (0.70) | ABL1BCRKITLYNCSF1R | |
| SCHEMBL13349541 | 0.93 | ABL1 (0.68) | ABL1BCRKITLYNCSF1R | |
| SCHEMBL14286281 | 0.93 | ABL1 (0.84) | ABL1BCRKITLYNCSF1R | |
| SCHEMBL3561586 | 0.91 | KIT (0.71) | ABL1BCRKITLYNCSF1R | |
| Hydrochloric Acid SCHEMBL6014047 | 0.91 | KIT (0.70) | ABL1BCRKITLYNCSF1R | |
| SCHEMBL715899 | 0.91 | KIT (0.85) | ABL1BCRKITLYNCSF1R | |
| SCHEMBL5025223 | 0.90 | BRAF (0.73) | ABL1BCRKITLYNCSF1R | |
| SCHEMBL6241566 | 0.86 | ABL1 (0.85) | ABL1BCRKITLYNCSF1R | |
| SCHEMBL717080 | 0.86 | ABL1 (0.80) | ABL1BCRKITLYNCSF1R | |
| SCHEMBL4833019 | 0.86 | ABL1 (0.80) | ABL1BCRKITLYNCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080025916-A1 | Tailored Treatment Suitable for Different Forms of Mastocytosis | AB SCIENCE | 2008-01-31 | — | — | US | disclosed |
| US-20080025916-A1 | Tailored Treatment Suitable for Different Forms of Mastocytosis | AB SCIENCE | 2008-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080025916-A1 | Tailored Treatment Suitable for Different Forms of Mastocytosis | KIT, CMA1, CPA3 | ABL1 8/4885BCR 41/4885KIT 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.