SCHEMBL14287343

SCHEMBL14287343

CCCCCN1C(=O)/C(=N/NC(N)=O)c2cc(SCCc3ccc(C(=O)O)cc3)ccc21

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PARK7 Q99497 1/20 0.39
RARB P10826 6/20 0.35
MCL1 Q07820 2/20 0.35
BCL2A1 Q16548 2/20 0.35
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35
RARA P10276 1/20 0.35
MAPT P10636 1/20 0.35
MTOR P42345 1/20 0.35
KMT2A Q03164 1/20 0.35
PLK1 P53350 1/20 0.35
PTGER4 P35408 1/20 0.35
PTGER2 P43116 1/20 0.35
CDC25A P30304 6/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5126019 1.00 PARK7 (0.39) PARK7RARBMCL1BCL2A1MEN1
SCHEMBL5118341 1.00 PARK7 (0.39) PARK7RARBMCL1BCL2A1MEN1
SCHEMBL5110144 0.96 RARB (0.37) PARK7RARBMEN1ALDH1A1RARA
SCHEMBL14287358 0.96 RARB (0.37) PARK7RARBMEN1ALDH1A1RARA
SCHEMBL5110149 0.96 RARB (0.37) PARK7RARBMEN1ALDH1A1RARA
SCHEMBL5126140 0.95 RARB (0.38) PARK7RARBMEN1ALDH1A1RARA
SCHEMBL14287353 0.95 RARB (0.38) PARK7RARBMEN1ALDH1A1RARA
SCHEMBL5119205 0.95 RARB (0.38) PARK7RARBMEN1ALDH1A1RARA
SCHEMBL5113483 0.94 PARK7 (0.40) PARK7MCL1BCL2A1MEN1KMT2A
SCHEMBL5113863 0.94 PARK7 (0.40) PARK7MCL1BCL2A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080004274-A1 Novel biaromatic compounds that modulate PPAR type receptors and cosmetic/pharmaceutical compositions comprised thereof GALDERMA RESEARCH & DEVELOPMENT (FR) 2008-01-03 US disclosed
US-20080004274-A1 Novel biaromatic compounds that modulate PPAR type receptors and cosmetic/pharmaceutical compositions comprised thereof GALDERMA RESEARCH & DEVELOPMENT (FR) 2008-01-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080004274-A1 Novel biaromatic compounds that modulate PPAR type receptors and cosmetic/pharmaceutical compositions comprised thereof PPARG, PPARD, PPARA PARK7 2430/4885RARB 37/4885MCL1 1860/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.