SCHEMBL1428736

SCHEMBL1428736

O=P(O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O)(O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O

nearest known ligand 0.62

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.47
▸ GAA P10253 1/20 0.46
▸ TYR P14679 1/20 0.46
▸ MAPT P10636 1/20 0.46
▸ PTPN1 P18031 2/20 0.45
▸ MEN1 O00255 1/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ IGF2R P11717 1/20 0.43
▸ LGALS1 P09382 2/20 0.42
▸ LGALS3 P17931 2/20 0.42
▸ LGALS9 O00182 1/20 0.42
▸ LGALS8 O00214 1/20 0.42
▸ POLB P06746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1521482 1.00 L3MBTL1 (0.47) L3MBTL1GAATYRMAPTPTPN1
SCHEMBL7549069 1.00 L3MBTL1 (0.47) L3MBTL1GAATYRMAPTPTPN1
SCHEMBL1521605 1.00 L3MBTL1 (0.47) L3MBTL1GAATYRMAPTPTPN1
SCHEMBL1521238 1.00 L3MBTL1 (0.47) L3MBTL1GAATYRMAPTPTPN1
SCHEMBL7085810 1.00 L3MBTL1 (0.47) L3MBTL1GAATYRMAPTPTPN1
SCHEMBL1428932 1.00 L3MBTL1 (0.47) L3MBTL1GAATYRMAPTPTPN1
SCHEMBL7550353 1.00 L3MBTL1 (0.47) L3MBTL1GAATYRMAPTPTPN1
SCHEMBL7547658 1.00 L3MBTL1 (0.47) L3MBTL1GAATYRMAPTPTPN1
SCHEMBL1521126 1.00 L3MBTL1 (0.47) L3MBTL1GAATYRMAPTPTPN1
SCHEMBL1521275 1.00 L3MBTL1 (0.47) L3MBTL1GAATYRMAPTPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116033941-A Pentavalent vaccine against neisseria meningitidis comprising synthetic MEN a antigen 葛兰素史克生物有限公司 2023-04-28 — — CN disclosed
US-20110104189-A1 COMPOSITIONS OBTAINED FROM CHLORELLA EXTRACT HAVING IMMUNOMODULATING PROPERTIES OCEAN NUTRITION CANADA LIMITED (CA) 2011-05-05 — — US disclosed
EP-2300026-A2 COMPOSITIONS OBTAINED FROM CHLORELLA EXTRACT HAVING IMMUNOMODULATING PROPERTIES Ocean Nutrition Canada Limited (CA) 2011-03-30 — — EP disclosed
US-7906460-B2 Active-site engineering of nucleotidylyltransferases and general enzymatic methods for the synthesis of natural and “unnatural” UDP- and TDP-nucleotide sugars SLOAN-KETTERING INSTITUTE FOR CANCER (US) 2011-03-15 — — US disclosed
WO-2009136296-A2 COMPOSITIONS OBTAINED FROM CHLORELLA EXTRACT HAVING IMMUNOMODULATING PROPERTIES OCEAN NUTRITION CANADA LIMITED (CA) 2009-11-12 — — WO disclosed
US-20070178487-A1 ACTIVE-SITE ENGINEERING OF NUCLEOTIDYLYLTRANSFERASES AND GENERAL ENZYMATIC METHODS FOR THE SYNTHESIS OF NATURAL AND \"UNNATURAL\" UDP- AND TDP-NUCLEOTIDE SUGARS WISCONSIN ALUMNI RESEARCH FOUNDATION 2007-08-02 — — US disclosed
US-7122359-B2 Active-site engineering of nucleotidylyltransferases and general enzymatic methods for the synthesis of natural and “unnatural” UDP- and TDP-nucleotide sugars SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 2006-10-17 — — US disclosed
US-20030055235-A1 Active-site engineering of nucleotidylyltransferases and general enzymatic methods for the synthesis of natural and \"unnatural\" UDP- and TDP-nucleotide sugars SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH 2003-03-20 — — US disclosed
WO-2002048331-A2 ACTIVE-SITE ENGINEERING OF NUCLEOTIDYLTRANSFERASES AND ENZYMATIC METHODS FOR THE SYNTHESIS OF NATURAL AND 'UNNATURAL' UDP- AND NUCLEOTIDE SUGARS MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2002-06-20 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030055235-A1 Active-site engineering of nucleotidylyltransferases and general enzymatic methods for the synthesis of natural and \"unnatural\" UDP- and TDP-nucleotide sugars PNP, NUDT14, ENTPD5 L3MBTL1 1097/4885GAA 305/4885TYR 1650/4885
US-20110104189-A1 COMPOSITIONS OBTAINED FROM CHLORELLA EXTRACT HAVING IMMUNOMODULATING PROPERTIES CD58, ALG1, C5 L3MBTL1 4660/4885GAA 1941/4885TYR 2699/4885
US-20070178487-A1 ACTIVE-SITE ENGINEERING OF NUCLEOTIDYLYLTRANSFERASES AND GENERAL ENZYMATIC METHODS FOR THE SYNTHESIS OF NATURAL AND \"UNNATURAL\" UDP- AND TDP-NUCLEOTIDE SUGARS PNP, NUDT14, NUDT5 L3MBTL1 1051/4885GAA 331/4885TYR 1571/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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