Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 10/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 10/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 10/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 9/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 9/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11623430 | 0.82 | HTR2A (0.44) | SIGMAR1HTR2AKCNH2HTR2CADRA1A | |
| SCHEMBL5395161 | 0.81 | SIGMAR1 (0.64) | SIGMAR1HTR2AKCNH2CHRM4CHRM5 | |
| SCHEMBL28270229 | 0.81 | SIGMAR1 (0.64) | SIGMAR1HTR2AKCNH2CHRM4CHRM5 | |
| SCHEMBL11413546 | 0.81 | SIGMAR1 (0.64) | SIGMAR1HTR2AKCNH2CHRM4CHRM5 | |
| SCHEMBL3769185 | 0.79 | CNR1 (0.46) | CNR1CNR2SCN5ASCN9AGAA | |
| SCHEMBL9540145 | 0.79 | BCL2 (0.47) | SIGMAR1HTR2AKCNH2HTR2CADRA1A | |
| SCHEMBL5159643 | 0.77 | SIGMAR1 (0.62) | SIGMAR1HTR2AKCNH2CHRM4CHRM5 | |
| SCHEMBL27797931 | 0.77 | CNR1 (0.42) | CNR1CNR2SCN5ASCN9AGAA | |
| Hydrochloric Acid SCHEMBL10512222 | 0.76 | CHRM4 (0.62) | SIGMAR1HTR2AKCNH2CHRM4CHRM5 | |
| SCHEMBL11329799 | 0.75 | CNR1 (0.44) | CNR1CNR2GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7320993-B1 | Aryl-substituted pyridylalkane, alkene, and alkine carboxamides useful as cytostatic useful as cytostatic and immuosuppressive agents | ASTELLAS DEUTSCHLAND GMBH (DE) | 2008-01-22 | — | — | US | disclosed |