Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 7/20 | 0.67 |
| ▸ | APP | P05067 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | BACE1 | P56817 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | RELA | Q04206 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.58 |
| ▸ | MAOA | P21397 | 2/20 | 0.58 |
| ▸ | MAOB | P27338 | 2/20 | 0.58 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.57 |
| ▸ | MMP9 | P14780 | 2/20 | 0.57 |
| ▸ | MMP1 | P03956 | 1/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9607191 | 0.87 | KDM1A (0.78) | KDM1AAPPMAPTBACE1MEN1 | |
| SCHEMBL9973848 | 0.86 | KDM1A (0.67) | KDM1AAPPMAPTBACE1MEN1 | |
| Curcumin SCHEMBL28389876 | 0.84 | BACE1 (0.78) | KDM1AAPPMAPTBACE1MEN1 | |
| SCHEMBL14429070 | 0.84 | KDM1A (0.62) | KDM1AAPPMAPTMAOAMAOB | |
| SCHEMBL23630641 | 0.83 | KDM1A (0.69) | KDM1AAPPMAPTBACE1MEN1 | |
| SCHEMBL4671925 | 0.83 | KDM1A (0.69) | KDM1AAPPMAPTBACE1MEN1 | |
| SCHEMBL30087650 | 0.83 | KDM1A (0.69) | KDM1AAPPMAPTBACE1MEN1 | |
| SCHEMBL29375351 | 0.83 | KDM1A (0.69) | KDM1AAPPMAPTBACE1MEN1 | |
| SCHEMBL14241952 | 0.83 | MEN1 (0.61) | KDM1AAPPMAPTMEN1NFKB1 | |
| SCHEMBL30087639 | 0.83 | KDM1A (0.69) | KDM1AAPPMAPTBACE1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1886662-A1 | Anti-microbial compounds for treating bad breath | Symrise GmbH & Co. KG (DE) | 2008-02-13 | — | — | EP | disclosed |