Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 7/20 | 0.78 |
| ▸ | MMP9 | P14780 | 4/20 | 0.67 |
| ▸ | MMP1 | P03956 | 3/20 | 0.67 |
| ▸ | MMP2 | P08253 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9607393 | 0.91 | MMP1 (0.67) | KDM1AMMP9MMP1MMP2MEN1 | |
| SCHEMBL13352244 | 0.91 | MEN1 (0.71) | KDM1AMMP9MMP1MMP2MEN1 | |
| SCHEMBL14290060 | 0.87 | KDM1A (0.67) | KDM1AMMP9MMP1MMP2MEN1 | |
| SCHEMBL20538352 | 0.87 | KDM1A (0.72) | KDM1AMMP9MMP1MMP2MEN1 | |
| SCHEMBL20538351 | 0.87 | KDM1A (0.72) | KDM1AMMP9MMP1MMP2MEN1 | |
| SCHEMBL13352028 | 0.86 | KDM1A (0.82) | KDM1AMMP9MMP1MMP2MEN1 | |
| SCHEMBL14319171 | 0.86 | ALDH1A1 (0.71) | KDM1AMMP9MMP1MMP2MEN1 | |
| SCHEMBL13352030 | 0.85 | PKM (0.59) | KDM1AMMP9MMP1MMP2MEN1 | |
| SCHEMBL13352031 | 0.85 | MMP1 (0.75) | KDM1AMMP9MMP1MMP2MEN1 | |
| SCHEMBL30568680 | 0.85 | KDM1A (1.00) | KDM1AMMP9MMP1MMP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120315233-A1 | ANTHRANILLIC ACID AMIDES AND DERIVATIVES THEREOF AS COSMETIC AND PHARMACEUTICAL ACTIVE COMPOUNDS | SYMRISE AG (DE) | 2012-12-13 | — | — | US | disclosed |
| WO-2012068612-A1 | METHODS OF TREATING EYE DISEASES ASSOCIATED WITH INFLAMMATION AND VASCULAR PROLIFERATION | FIBROTECH THERAPEUTICS PTY LTD (AU) | 2012-05-31 | — | — | WO | disclosed |
| WO-2008131481-A1 | TREATMENT OF MESANGIOPROLIFERATIVE DISEASES | FIBROTECH THERAPEUTICS PTY LTD (AU) | 2008-11-06 | — | — | WO | disclosed |
| EP-1886662-A1 | Anti-microbial compounds for treating bad breath | Symrise GmbH & Co. KG (DE) | 2008-02-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120315233-A1 | ANTHRANILLIC ACID AMIDES AND DERIVATIVES THEREOF AS COSMETIC AND PHARMACEUTICAL ACTIVE COMPOUNDS | CMA1, TPSAB1, HRH1 | KDM1A 362/4885MMP9 606/4885MMP1 149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.