Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 16/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL836953 | 0.92 | MEN1 (0.41) | METHTTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL14291812 | 0.82 | MET (0.48) | MET | |
| SCHEMBL1950806 | 0.82 | L3MBTL1 (0.43) | METHTTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL835534 | 0.81 | MET (0.43) | MET | |
| SCHEMBL14291363 | 0.79 | MET (0.43) | MET | |
| SCHEMBL14291482 | 0.79 | MET (0.42) | MET | |
| SCHEMBL14291362 | 0.79 | MET (0.46) | MET | |
| SCHEMBL836456 | 0.78 | MET (0.48) | MET | |
| SCHEMBL836630 | 0.78 | MET (0.46) | MET | |
| SCHEMBL835350 | 0.78 | MET (0.44) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021781-A1 | TRIAZOLOTRIAZINES AS KINASE INHIBITORS | INCYTE CORPORATION (US) | 2008-02-21 | — | — | WO | disclosed |