Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.56 |
| ▸ | NSD2 | O96028 | 2/20 | 0.56 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.55 |
| ▸ | ITGAM | P11215 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21760925 | 0.79 | MEN1 (0.63) | LCKPOLBMAPTKMT2AMEN1 | |
| SCHEMBL29466154 | 0.78 | APEX1 (0.66) | LCKPOLBMAPTKMT2AMEN1 | |
| SCHEMBL3894511 | 0.78 | APEX1 (0.66) | LCKPOLBMAPTKMT2AMEN1 | |
| SCHEMBL3894518 | 0.78 | APEX1 (0.66) | LCKPOLBMAPTKMT2AMEN1 | |
| SCHEMBL3895627 | 0.75 | POLB (0.72) | POLBMAPTKMT2AMEN1TDP1 | |
| SCHEMBL3895634 | 0.75 | POLB (0.72) | POLBMAPTKMT2AMEN1TDP1 | |
| SCHEMBL15374280 | 0.75 | POLB (0.72) | POLBMAPTKMT2AMEN1TDP1 | |
| SCHEMBL14426457 | 0.75 | LCK (1.00) | LCKPOLBMAPTKMT2AMEN1 | |
| SCHEMBL14426569 | 0.75 | KMT2A (0.76) | LCKPOLBMAPTKMT2AMEN1 | |
| SCHEMBL25865503 | 0.75 | LCK (1.00) | LCKPOLBMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008024759-A2 | IMMUNOMODULATORY COMPOUNDS THAT TARGET AND INHIBIT THE PY+3 BINDING SITE OF TYROSENE KINASE P56 LCK SH2 DOMAIN | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2008-02-28 | — | — | WO | disclosed |