Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.63 |
| ▸ | RAB9A | P51151 | 5/20 | 0.63 |
| ▸ | NPC1 | O15118 | 4/20 | 0.63 |
| ▸ | POLB | P06746 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.53 |
| ▸ | ITGAM | P11215 | 3/20 | 0.53 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | MYC | P01106 | 1/20 | 0.48 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL46557 | 0.86 | MEN1 (0.70) | MEN1KMT2ARAB9ANPC1POLB | |
| SCHEMBL2302382 | 0.83 | KMT2A (0.62) | MEN1KMT2ARAB9ANPC1POLB | |
| SCHEMBL2302380 | 0.83 | KMT2A (0.62) | MEN1KMT2ARAB9ANPC1POLB | |
| SCHEMBL12177202 | 0.82 | ALDH1A1 (0.60) | MEN1KMT2ARAB9ANPC1POLB | |
| SCHEMBL12177177 | 0.81 | ENPP2 (0.64) | MEN1KMT2ARAB9APOLBALDH1A1 | |
| SCHEMBL3895634 | 0.80 | POLB (0.72) | MEN1KMT2ARAB9ANPC1POLB | |
| SCHEMBL3895627 | 0.80 | POLB (0.72) | MEN1KMT2ARAB9ANPC1POLB | |
| SCHEMBL15374280 | 0.80 | POLB (0.72) | MEN1KMT2ARAB9ANPC1POLB | |
| SCHEMBL14291863 | 0.79 | LCK (0.59) | MEN1KMT2ARAB9ANPC1POLB | |
| SCHEMBL29665060 | 0.79 | LCK (0.73) | MEN1KMT2ARAB9ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3243821-B1 | PHARMACEUTICAL FORMULATIONS FOR REGULATING INTEGRIN CD11B/CD18 | GB006 INC (US) | 2020-02-26 | — | — | EP | disclosed |