Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 1.00 |
| ▸ | GSK3A | P49840 | 1/20 | 0.59 |
| ▸ | GSK3B | P49841 | 1/20 | 0.59 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 9/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.54 |
| ▸ | POLB | P06746 | 8/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14426457 | 1.00 | LCK (1.00) | LCKGSK3AGSK3BAPEX1PIK3CG | |
| SCHEMBL29908306 | 0.89 | LCK (0.80) | LCKGSK3AGSK3BAPEX1PIK3CG | |
| SCHEMBL14426540 | 0.88 | LCK (0.78) | LCKGSK3AGSK3BAPEX1PIK3CG | |
| SCHEMBL29665060 | 0.84 | LCK (0.73) | LCKGSK3AGSK3BAPEX1PIK3CG | |
| SCHEMBL29415356 | 0.83 | LCK (0.71) | LCKGSK3AGSK3BAPEX1PIK3CG | |
| SCHEMBL6795412 | 0.82 | APEX1 (0.70) | LCKGSK3AGSK3BAPEX1PIK3CG | |
| SCHEMBL14426549 | 0.81 | MEN1 (0.76) | LCKGSK3AGSK3BAPEX1PIK3CG | |
| SCHEMBL3892650 | 0.81 | APEX1 (0.71) | LCKGSK3AGSK3BAPEX1PIK3CG | |
| SCHEMBL3892654 | 0.81 | APEX1 (0.71) | LCKGSK3AGSK3BAPEX1PIK3CG | |
| SCHEMBL3896597 | 0.81 | LCK (0.68) | LCKGSK3AGSK3BAPEX1PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230233696-A1 | TRIANTENNARY N-ACETYLGALACTOSAMINE MODIFIED HYDROXYL POLYAMIDOAMINE DENDRIMERS AND METHODS OF USE THEREOF | Ashvattha Therapeutics, Inc. (US) | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230233696-A1 | TRIANTENNARY N-ACETYLGALACTOSAMINE MODIFIED HYDROXYL POLYAMIDOAMINE DENDRIMERS AND METHODS OF USE THEREOF | FUT6, FUT5, OGT | LCK 4173/4885GSK3A 2026/4885GSK3B 2130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.