Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | TERT | O14746 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 6/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15338362 | 1.00 | TNKS (0.53) | TNKSCYP19A1ACHETERTMAOB | |
| SCHEMBL1483628 | 0.95 | PRKDC (0.52) | ACHETERTMAOBTDP1NPC1 | |
| SCHEMBL1483630 | 0.95 | PRKDC (0.52) | ACHETERTMAOBTDP1NPC1 | |
| SCHEMBL1483626 | 0.95 | PRKDC (0.52) | ACHETERTMAOBTDP1NPC1 | |
| SCHEMBL4406416 | 0.90 | MAOB (0.56) | TNKSCYP19A1ACHEMAOBKDM4E | |
| SCHEMBL4408510 | 0.83 | CYP1A1 (0.52) | ACHETERTMAOBTDP1NPC1 | |
| SCHEMBL10486553 | 0.83 | TNKS (0.61) | TNKSCYP19A1KDM4ECYP3A4SMN1; SMN2 | |
| SCHEMBL4414243 | 0.79 | PABPC1 (0.60) | TNKSCYP19A1ACHEMAOBKDM4E | |
| SCHEMBL12829688 | 0.79 | CYP3A4 (0.50) | TNKSCYP19A1TERTMAOBMAOA | |
| SCHEMBL12829683 | 0.79 | CYP3A4 (0.50) | TNKSCYP19A1TERTMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018089-A1 | R-(-) / S-(+)-7-[3-N-SUBSTITUTED AMINO-2-HYDROXYPROPOXY] FLAVONES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2008-02-14 | — | — | WO | disclosed |