Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.60 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.54 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.52 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.52 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | TNKS | O95271 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4405402 | 0.89 | ABCB1 (0.69) | ABCB1CSNK2A2CSNK2BCSNK2A1MAOB | |
| SCHEMBL4406416 | 0.88 | MAOB (0.56) | ABCB1MAOBTNKSCYP19A1BCHE | |
| SCHEMBL6555693 | 0.83 | PABPC1 (0.76) | PABPC1ABCB1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL4405490 | 0.83 | PABPC1 (0.63) | PABPC1ABCB1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL12829688 | 0.82 | CYP3A4 (0.50) | PABPC1ABCB1MAOBTNKSCYP19A1 | |
| SCHEMBL12829683 | 0.82 | CYP3A4 (0.50) | PABPC1ABCB1MAOBTNKSCYP19A1 | |
| SCHEMBL10486553 | 0.82 | TNKS (0.61) | TNKSCYP19A1KDM4ECYP3A4SMN1; SMN2 | |
| SCHEMBL4411697 | 0.81 | PABPC1 (0.64) | PABPC1ABCB1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL10814110 | 0.80 | TERT (0.53) | MAOBTNKSKDM4EALDH1A1HPGD | |
| SCHEMBL14293137 | 0.79 | TNKS (0.53) | MAOBTNKSCYP19A1ACHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807408-B1 | OXY SUBSTITUTED FLAVONES AS ANTIHYPERGLYCEMIC AND ANTIDYSLIPIDEMIC AGENTS | COUNCIL SCIENT IND RES (IN) | 2016-06-08 | — | — | EP | disclosed |
| US-7635779-B2 | Oxy substituted flavones as antihyperglycemic and antidyslipidemic agents | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-12-22 | — | — | US | disclosed |
| EP-1807408-A1 | OXY SUBSTITUTED FLAVONES AS ANTIHYPERGLYCEMIC AND ANTIDYSLIPIDEMIC AGENTS | Council of Scientific and Industrial Research (IN) | 2007-07-18 | — | — | EP | disclosed |
| US-20060178373-A1 | Oxy substituted flavones as antihyperglycemic and antidyslipidemic agents | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2006-08-10 | — | — | US | disclosed |
| WO-2006040621-A1 | OXY SUBSTITUTED FLAVONES AS ANTIHYPERGLYCEMIC AND ANTIDYSLIPIDEMIC AGENTS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-04-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060178373-A1 | Oxy substituted flavones as antihyperglycemic and antidyslipidemic agents | GPR119, LIPC, SLC5A2 | PABPC1 4790/4885ABCB1 1033/4885CSNK2A2 3178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.