Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.49 |
| ▸ | LMNA | P02545 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 8/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HBB | P68871 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | JAK2 | O60674 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8823870 | 0.79 | MAPT (0.49) | MAPTLMNAALDH1A1HTTPOLB | |
| SCHEMBL3192831 | 0.79 | MAPT (0.61) | MAPTLMNAALDH1A1HTTPOLB | |
| SCHEMBL11765388 | 0.73 | MAPT (0.46) | MAPTLMNAALDH1A1HTTPOLB | |
| SCHEMBL8482509 | 0.65 | LMNA (0.55) | MAPTLMNAALDH1A1HTTPOLB | |
| SCHEMBL861476 | 0.65 | MAPT (0.57) | MAPTLMNAALDH1A1HTTPOLB | |
| SCHEMBL15825843 | 0.65 | PTGS1 (0.42) | MAPTLMNAALDH1A1HTTPOLB | |
| SCHEMBL16339857 | 0.64 | LMNA (0.53) | MAPTLMNAALDH1A1HTTPOLB | |
| SCHEMBL13849452 | 0.64 | MAPT (0.46) | MAPTLMNAALDH1A1HTTPOLB | |
| SCHEMBL64091 | 0.63 | ALDH1A1 (0.42) | MAPTLMNAALDH1A1HTTPOLB | |
| SCHEMBL13408654 | 0.62 | MAPT (0.74) | MAPTLMNAALDH1A1HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008024364-A2 | HETEROCYCLIC COMPOUNDS AS SWEETENER ENHANCERS | REDPOINT BIO CORPORATION (US) | 2008-02-28 | — | — | WO | disclosed |